نتایج جستجو برای: myocardial enzyme
تعداد نتایج: 393431 فیلتر نتایج به سال:
Abstract: Background: Streptokinase has been widely prescribed as a fibrinolytic agent for myocardial infarction. Simple structural characteristics of this protein have provided techniques for production of different recombinant types of this protein. The present study was designed to prepare equisimilisH46A subtype of streptokinase in our country. Materials and methods: Having extracted the...
Inhibition of the renin-angiotensin system has been shown to improve symptoms and prognosis in heart failure. We compared the effects of inhibition of angiotensin-converting enzyme or blockade of angiotensin II type 1 (AT1) receptors in a model with renin-induced hypertension that is known to exhibit similar changes in sympathetic activation and beta-adrenergic desensitization, as observed in h...
BACKGROUND The effect on cardiovascular outcomes of withholding angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers in chronic users before noncardiac surgery is unknown. METHODS In this international prospective cohort study, the authors analyzed data from 14,687 patients (including 4,802 angiotensin-converting enzyme inhibitor/angiotensin II receptor blocker users) ...
BACKGROUND Free radical injury contributes to cardiac dysfunction during ischemia-reperfusion. Detoxification of free radicals requires maintenance of reduced glutathione (GSH) by NADPH. The principal mechanism responsible for generating NADPH and maintaining GSH during periods of myocardial ischemia-reperfusion remains unknown. Glucose-6-phosphate dehydrogenase (G6PD), the rate-limiting enzyme...
1.Elliott, B. A., and Wilkinson, J. H., Serum “a-hydroxybutyrate dehydrogenase” in myocardial infarction and in liver disease. Lancet i, 698(1961). 2. Elliott, B. A., Jepson, E. M., and Wilkinson, J. H., Serum ahydroxybutyrate dehydrogenase-a new testwith improved specificity for myocardial lesions. Gun. Sci. 23, 305(1962). 3. Coodley, E. L., Evaluation of enzyme diagnosis in myocardial infarct...
The effects of the angiotensin converting enzyme inhibitor enalapril on myocardial sympathetic tone, as represented by noradrenaline overflow, were studied in 14 men with congestive heart failure (mean ejection fraction 20%) in a double blind crossover comparison with placebo. Arterial and coronary sinus catecholamine concentrations and oxygen content, and coronary sinus blood flow, were measur...
BACKGROUND The heart is a tumor necrosis factor-alpha (TNF-alpha)-producing organ. Recent basic experimental and clinical evidence suggests that TNF-alpha is an important mediator of myocardial injury during acute myocardial infarction, chronic heart failure, cardiac allograft rejection, and cardiopulmonary bypass operations. Although it is known that the myocardium itself is capable of produci...
Oxidative stress is defined as an imbalance between the antioxidant defense system and production of reactive oxygen species (ROS). At low levels, ROS are involved in regulation redox signaling for cell protection. However, upon chronical increase oxidative stress, damage occurs, due to protein, DNA lipid oxidation. Here, we investigated modifications myofilament proteins, their role modulating...
649 Abstract: Cardiac Troponin T (TnT) is a regulatory contractile protein not normally found in blood. Its detection in the circulation has been shown to be a sensitive and specific marker for myocardial cell damage. This study was designed to evaluate the diagnostic efficiency of TnT enzyme immunoassay in detecting myocardial damage in patients with stable angina pectoris undergoing visually ...
SARS-CoV-2 has driven the COVID-19 epidemic around world, making it one of most significant medical challenges last century. This infectious agent infects host cells by binding to ACE2 receptors (an enzyme present in several tissues, such as heart, lung and kidneys) can lead pneumonia, acute myocardial damage chronic cardiovascular system. Pre-existing conditions diabetes, hypertension obesity ...
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