OBJECTIVE Diabetes and obesity are associated with increased plasma nonesterified fatty acid (NEFA) levels, myocardial triglyceride accumulation, and myocardial dysfunction. Because a very low-calorie diet (VLCD) also increases plasma NEFA levels, we studied the effect of a VLCD on myocardial triglyceride content and cardiac function in healthy subjects. RESEARCH DESIGN AND METHODS Fourteen h...

Cardiovascular magnetic resonance (CMR) is currently the gold standard for assessing both global and regional myocardial function. New tools for quantifying regional function have been recently developed to characterize early myocardial dysfunction in order to improve the identification and management of individuals at risk for heart failure. Of particular interest is CMR myocardial tagging, a ...

The thickness of epicardial adipose tissue (EAT) has the potential to act as a novel indicator cardiac and visceral adiposity its function in myocardial infarction (MI) diagnosis therapy.

Background T2-weighted edema imaging identifies the ischemic area at risk during acute myocardial infarction. Myocardial salvage occurs in the area at risk without late gadolinium enhancement (LGE). The degree of myocardial salvage is prognostically important, but its effect on recovery of left ventricular (LV) function is not known. The purpose of this study was to determine if the degree of m...

Introduction: Asymptomatic diabetic patients are at increased risk of cardiovascular complications. Myocardial perfusion scan may be effective in risk evaluation in this population. Methods: 106 asymptomatic diabetic patients (age: min: 37, max: 82, mean: 57.73±8.88), including 56 females (52.8%) and 50 males (47.2%) were enrolled in the study. Myocardial perfusion scintigraphy was performed b...

background: the aim of this study was to echocardiographically assess the effects of eecp (enhanced external counterpulsation therapy) therapy on systolic and diastolic cardiac function. methods: lvef (left ventricular ejection fraction), esv (end-systolic volume), edv (end-diastolic volume), sm (myocardial systolic wave) , ea (myocardial early diastolic wave), vp (propagation velocity), e/ea (...

BACKGROUND Myocardial ischemia is an important determinant of regional left ventricular systolic function. Myocardial blood flow reserve may be impaired by cardiovascular disease before alterations of myocardial perfusion at rest become manifest. Nevertheless, the relation between flow reserve and regional myocardial function has not been studied in individuals without a history of clinical hea...

OBJECTIVE To evaluate the effects of hyperglycemia due to partial insulin deprivation on myocardial triglyceride (TG) content and myocardial function in patients with type 1 diabetes. RESEARCH DESIGN AND METHODS Myocardial and hepatic TG content and left ventricular (LV) function were measured by magnetic resonance (MR) spectroscopy and MR imaging during optimal glucoregulation and after 24 h...

conclusion osem3d may provide better image quality and higher contrast than other methods for small animal imaging with the new myocardial imaging agent, [18f] fptp. results the location and size of myocardial infarction on pet images correlated closely with that observed with ttc staining. among the four reconstruction methods, osem3d provided the best assessment of infarct size (r2 = 0.994, p...

myocardial free wall rupture is a catastrophic complication of acute myocardial infarction, and prognosis will depend on the prompt diagnosis by echocardiography, extension of infarct size, and prompt surgical treatment. free wall rupture concomitant with ventricular septal defect (vsd) may be more complicated for management. a case of a 69-year-old man with myocardial free wall rupture and vsd...