Introduction The pathophysiology of chest pain in patients with Syndrome X remains controversial. Previous studies using nuclear techniques or CMR to assess myocardial perfusion have shown conflicting results. Advances in perfusion imaging with CMR now enable absolute quantification of regional myocardial blood flow. Furthermore, blood oxygenation level-dependent (BOLD) CMR provides the unprece...

Background Myocardial perfusion single photon emission computed tomography (MPS) and cardiac magnetic resonance (CMR) can be used for assessment of myocardial ischemia. The methods reveal different aspects of the pathophysiology associated with myocardial ischemia where MPS is based on uptake of a perfusion tracer in viable mitochondria whereas CMR is based on firstpass perfusion reflecting cor...

OBJECTIVE This retrospective study aimed to investigate the relationship between admission levels of serum y-glutamyltransferase and poor myocardial perfusion after primary percutaneous coronary intervention in patients with acute myocardial infarction. INTRODUCTION Reperfusion injury caused by free radical release and increased oxidative stress is responsible for the pathophysiology of the n...

Myocardial involvement is an important prognostic factor in patients with systemic sclerosis, and early diagnosis and staging of the disease have been sought after. Since myocardial damage is characterized by connective tissue disease, including fibrosis and diffuse vascular lesions or microcirculation, nuclear myocardial perfusion imaging has been a promising option for evaluating myocardial d...

1. Perfusion imaging to detect myocardial ischemia Myocardial ischemia occurs when insufficient blood flow, or perfusion, to the myocardium results in inadequate delivery of oxygen as well as inadequate removal of metabolites. These conditions may occur at rest due to insufficient oxygen supply (supply ischemia) or at stress due to a failure to sufficiently accommodate increased oxygen demand (...