Objectives: Exercise intolerance and peripheral muscle dysfunction are important consequence of cystic fibrosis (CF) Systemic inflammation, oxidative stress, physical inactivity responsible for decreased exercise capacity impaired function. A newly myokine called irisin seem to increased oxygen consumption energy supply. This study was aimed investigate the relationship between serum concentrat...

Background: Irisin is a recent myokine that decreases obesity and enhances insulin resistance by converting white adipose tissues to brown, leading increase thermogenesis lower resistance. Objective: The impact of moderate swimming exercise combined with dietary vitamin D on serum irisin levels was evaluated in type II diabetes rat model (T2DM). Material Methods: This study conducted between Se...

Intestinal alkaline phosphatase (IAP) is an essential mucosal defense factor involved in the process of maintenance gut homeostasis. We determined effect moderate exercise (voluntary wheel running) with or without treatment IAP on course experimental murine 2,4,6-trinitrobenzenesulfonic acid (TNBS) colitis by assessing disease activity index (DAI), colonic blood flow (CBF), plasma myokine irisi...

Background: Irisin is a recently identified myokine that acts like adipokines. It has been revealed to be connected with insulin resistance (IR), obesity, and metabolic syndrome. Objective: To investigate serum, follicular fluid (FF), irisin, IR in lean, overweight, obese women undergoing the intracytoplasmic sperm injection (ICSI) cycle correlate them oocyte embryo quality. Methods: Ninety inf...