OBJECTIVE To report clinical features, response to treatment, and long-term follow-up of nail lichen planus in children. DESIGN Retrospective study involving 15 children with nail lichen planus. SETTING Outpatient consultation for nail disorders at the Department of Dermatology of the University of Bologna, Bologna, Italy. PATIENTS OR OTHER PARTICIPANTS We diagnosed nail lichen planus in ...

Background and Purpose: Tinea capitis and tinea unguium are regarded as global public health concerns. The purpose of the present study was to identify the etiological agents of tinea capitis and tinea unguium in patients, referring to the Central Laboratory of Yazd University of Medical Sciences, Yazd, Iran. Materials and Methods: This study was conducted during 2014-2015. Skin scraping, scal...

The nail is a specialized keratinous skin appendage that grows approximately 2 to 3 mm per month, with complete replacement achieved in 6 to 9 months. Although this structure can be easily overlooked, nail disorders comprise approximately 10% of all dermatologic conditions. This contribution first provides an overview on the basic anatomy of the nail that will delineate between the nail unit (e...

Background / Objectives:Dermoscopy is a non-invasive technique that has been recognized recently as an effective tool in the diagnosis of nail diseases, including psoriasis. The aim this study was to clarify specific dermoscopic features psoriasis and identify those are correlated with disease severity. Methods: We conducted prospective over 18 months. Fifty patients followed for involvement we...

Nail dermoscopy was initially used only in the assessment of nail pigmentation, but now it is widely utilized for the evaluation of many nail disorders. In daily practice, dermoscopy may confirm clinical diagnoses and guides in the management of nail diseases and treatments, permitting a better visualization of symptoms. Dry dermoscopy is required for evaluation of the nail plate surface, while...

The nail unit is a dynamic complex which forms an important part of the integument. This complex consists of the nail matrix (NM), nail bed (NB), hyponychium, nail fold (NF) and the nail plate (NP). Cells of the nail matrix, under the protection of the proximal nail fold mature and keratinised to form the NP. The NM contributes to the most portion of the NP while about 10-15% is produced by the...

OBJECTIVE (1) To compare clinical characteristics of patients with psoriatic arthritis (PsA) with PsA mutilans (PAM) and without PAM, and (2) to determine the rate of PAM radiographic progression. METHODS A retrospective cohort study was conducted of all patients with PsA attending a teaching hospital. The most recent hand and feet radiographs were screened for PAM. Serial radiographs (earlie...

Regulation of adult stem cells (SCs) is fundamental for organ maintenance and tissue regeneration. On the body surface, different ectodermal organs exhibit distinctive modes of regeneration and the dynamics of their SC homeostasis remain to be unraveled. A slow cycling characteristic has been used to identify SCs in hair follicles and sweat glands; however, whether a quiescent population exists...

Examination and surgical intervention of nail unit lesions are often hindered by its natural hard keratinous nail plate. Knowledge of the basic anatomy of a nail unit and surgical pathology of a condition facilitate the delivery of an appropriate and effective treatment. The mild form of common ingrown toenail can be managed by tube insertion which entails inserting without anaesthesia a small ...