Yellow nail syndrome (YNS) is a rare entity of unknown cause in which congenitally hypoplastic lymphatics play a major role in the clinical manifestations of the disease. YNS has been associated with many malignancies and immune disorders. We report a case of new-onset YNS associated with breast cancer and dramatic improvement in the yellow nails with cancer treatment.

This article presents new intramedullary (IM) nail design for femur diaphyseal fractures osteosynthesis. Biomechanical comparison of the two IM nails (standard locking and new developed) was conducted. Femur medullary canal architectonics was studied with the help of computer tomography (CT) data. Three-dimensional (3D) models of the femur, its transverse fracture, standard locking nail and new...

BACKGROUND: Etanercept is a fully human tumor necrosis factor a receptor fusion protein that binds tumor necrosis factor a with greater affinity than natural receptors. Biologics are widely used in the treatment of psoriasis and psoriasis arthritis and may represent a new therapeutic option for some patients with psoriatic nail disease. CASE REPORT: We report a case of lichen planus limited to ...

OBJECTIVE To assess the extent to which UV-A and UV-B radiation can penetrate the human fingernail plate. DESIGN The Dermalite UV light machine (National Biological, Beachwood, Ohio) was used as the source of UV radiation. The amount of UV-A and UV-B penetrating the nail plate was measured using a radiometer and compared with a control. SETTING Academic phototherapy clinic. PATIENTS Ten c...

BACKGROUND Chronic renal failure affects almost all the systems of the body, including the skin and appendages. The nail disorders most commonly found in patients with chronic renal failure are half and half nails, absent lunula and splinter hemorrhages. OBJECTIVES To evaluate the spectrum and the frequency of nail disorders in patients with chronic renal failure submitted to hemodialysis and...

OBJECTIVES To study the frequency of nail changes in a population of human immunodeficiency virus (HIV)-infected patients and to evaluate the specificity of these findings by comparison with HIV-negative control subjects. DESIGN Prospective controlled study. Nail changes were recorded by a standardized clinical examination (curvature, nail plate, color, onychomycosis). In case of clinical dia...

OBJECTIVES Lower-extremity vascular diseases are important complication of diabetes. In the present study, we investigated the influence of blood glucose fluctuation in type 2 diabetes-associated lower-extremity vascular diseases, and explore the possible mechanism. PATIENTS AND METHODS Patients with type 2 diabetes was assigned to Group B (without lower-extremity vascular disease) and group ...

Congenital alopecia universalis is one of the rarest anomaly which involves skin and appendages. The inheritance pattern can be autosomal recessive, X-linked recessive, or autosomal dominant. However, the most common is autosomal recessive form and it is the most severe phenotype. Twenty-nail dystrophy refers to the condition in which all the twenty nails are affected in the form of excessive r...