Human exposure to nanomaterials and nanoparticles is increasing rapidly, but their effects on human health are still largely unknown. Epigenetic modifications are attracting ever more interest as possible underlying molecular mechanisms of gene-environment interactions, highlighting them as potential molecular targets following exposure to nanomaterials and nanoparticles. Interestingly, recent ...

objective(s): this study was aimed at investigating the synergy effects of aloe vera gel and silver nanoparticles on the healing rate of the cutting wounds. materials and methods: in order to determine the concentration of silver nanoparticles in aloe vera gel, the mbc methods were applied on the most common bacteria infecting wounds, staphylococcus aureus, escherichia coli, pseudomonas aerugin...

To date, the effects of nanoparticles on woody plants remain unaddressed. This study reveals some of the physiological and biochemical effects of SiO2 nanoparticles on wild pear seedlings. The seedlings were irrigated with different concentrations of nano silica (0, 10, 100, 500 and 1000 mg/l) for 14 days. Nanoparticle adsorption and absorption, biomass allocation, gas exchange, relative water ...

Microsomal glutathione transferase 1 (MGST1) is an antioxidant enzyme located predominantly in the mitochondrial outer membrane and endoplasmic reticulum and has been shown to protect cells from lipid peroxidation induced by a variety of cytostatic drugs and pro-oxidant stimuli. We hypothesized that MGST1 may also protect against nanomaterial-induced cytotoxicity through a specific effect on li...

Engineered nanoparticles are becoming increasingly incorporated into technology and consumer products. In 2014, over 300 tons of copper oxide nanoparticles were manufactured in the United States. The increased production of nanoparticles raises concerns regarding the potential introduction into the environment or human exposure. Copper oxide nanoparticles commonly release copper ions into solut...

in this study chemical method of dissolution-precipitation was applied to produce amorphous silica nanoparticles from rice straw ash (rsa), the waste material of rice cultivation. the morphology, particle size, structure and area of specific surface of synthesized amorphous silica nanoparticles were evaluated using transmission electron microscopy (tem), x-ray diffraction analysis (xrd) and bet...

this article presents an experimental investigation on effects of morphology of nanoparticles on the viscosity nanofluids (nfs). water and ethylene glycol were used as base fluids. a two step method was used for preparation of nfs. sio2 nanoparticles, cnt and graphene nano sheets were dispersed in the base fluids separately with the volume fraction ranging from 0.05% to 1.5%. stability of the n...

Carbon nanoparticles, with their high biocompatibility and low toxicity, have recently been considered for biomedical applications, including antiangiogenic therapy. Critical to normal development and tumor formation, angiogenesis is the process of forming capillary blood vessels from preexisting vessels. In the present study, we evaluated the effects of diamond and graphite nanoparticles on th...

Amphotericin B (AmB)/poly(lactic acid)-b-poly(ethylene glycol) (PLA-b-PEG) nanoparticles coated with polysorbate 80 (Tween-80) were prepared by nanoprecipitation for transport across the blood-brain barrier (BBB). The effects of Tween-80 on the size and distribution, entrapment efficiency and release behavior of AmB/PLA-b-PEG nanoparticles were investigated. Furthermore, the brain targeting and...