The aim of this study was to objectively evaluate the effects of intranasal therapy with azelastine (AZE), budesonide (BUD), and combined AZE plus BUD (AZE/BUD) using a nasal provocation test (NPT) and acoustic rhinometry in patients with allergic rhinitis. A randomized, single-blind, crossover study with three treatment sequences was used. Thirty patients with persistent AR received the three ...

OBJECTIVE To compare the efficacy of ketorolac nasal spray (NS) vs. placebo and sumatriptan NS for the acute treatment of migraine. METHODS This was a randomized, double-blind, placebo and active-comparator, crossover study. Adult migraineurs were randomized to ketorolac NS 31.5 mg, sumatriptan NS 20 mg, or placebo to treat three moderate to severe migraine attacks and switched treatments wit...

conclusions it seems that nasal spray of calcitonin can effectively improve qol of women with lbd and qol changes were not influenced by clinical or para-clinical alteration. mental health domain must be more considered in further studies as a predicting domain for health-related quality of life (hr-qol) changes. background physical activity and mental health could be affected by osteoporosis a...

OBJECTIVES Determining Staphylococcus aureus nasal carriage, antibiotic susceptibility and association with potential risk factors in residents from the Hogar Asilo de Ancianos San Pedro Claver nursing-home in Cartagena during the second semester of 2007. METHODS Nasal swabs were taken from each person participating in the study after they had signed an informed consent form. Staphylococcus a...

OBJECTIVE Smoking topography refers to how a person smokes a cigarette and includes measures of the number of puffs and puff volume, duration, and velocity. This study examined the relationship between smoking topography and abstinence from cigarettes following nicotine replacement therapy. A secondary objective was to determine the relationship of smoking topography to carbon monoxide (CO) exp...

OBJECTIVES The aim of this study was to determine whether nicotine, a constituent of cigarette smoke, contributes to acute endothelial dysfunction after smoking one cigarette. BACKGROUND Animal studies suggest that nicotine might cause an impairment of endothelium-dependent vasodilation via an increase in oxidative stress. METHODS Sixteen healthy smokers were entered into a randomized, obse...

Topical steroids are widely used in the treatment of allergic rhinitis and have recently become available as an over-the-counter product (Beconase nasal spray). They are considered safe since it is believed that they are not absorbed in large enough quantities to have systemic effects. Reports of adverse effects relating to their use are rare.' We report a case of iatrogenic Cushing's syndrome ...