camptomelic dysplasia (cmd) is a rare autosomal dominant congenital dwarfism characterized by shortness and bowing of long bones (camptomelia) and other severe skeletal and extra skeletal malformations. cmd is generally considered to be lethal and the majority of cases die in the neonatal period due to respiratory insufficiency. we hereunder report a term male neonate with characteristic clinic...

AIM Providing consistent levels of oxygen saturation (SpO2 ) for infants in neonatal intensive care units is not easy. This study explored how effectively the Auto-Mixer(®) algorithm automatically adjusted fraction of inspired oxygen (FiO2 ) levels to maintain SpO2 within an intended range in extremely low birth weight infants receiving supplemental oxygen without mechanical ventilation. METH...

BACKGROUND The efficiency of routine practices in the management of neonatal respiratory distress syndrome (RDS) have never been systematically investigated in Poland. OBJECTIVE To evaluate RDS treatment policies and short-term outcomes in neonatal intensive care units (NICUs). MATERIAL AND METHODS We retrospectively analyzed medical records of premature neonates ≤ 32 weeks' gestation, diag...

INTRODUCTION Intensive care of infants below one year of age has been centralized in a paediatric intensive care unit (PICU) related to the neonatal intensive care unit (NICU) at Rigshospitalet, the University Hospital in Copenhagen in eastern Denmark (approximately 2.5 million inhabitants) since 2002. The aim of this paper was to evaluate the experiences from the PICU. MATERIAL AND METHODS A...

OBJECTIVES To examine the characteristics of incidents reported after introduction of a voluntary, non-punitive incident reporting system for neonatal intensive care units (NICUs) in the Netherlands; and to investigate which types of reported incident pose the highest risk to patients in the NICU. DESIGN Prospective multicentre survey. METHODS Voluntary, non-punitive incident reporting was ...

variability of tidal volume and respiratory rate in normally breathing man has long been demonstrated [1]. however because of lack of knowledge and technology primary ventilators could only deliver a fixed tidal volume in a fixed rate the so called volume controlled ventilation (vcv). vcv was volume preset time triggered and cycled and there was no synchronization with patient’s breaths. at tha...

BACKGROUND In neonatal respiratory distress syndrome (RDS) and acute RDS (ARDS) mechanical ventilation is often necessary to manage hypoxia, whilst protecting the lungs through lower volume ventilation and permissive hypercapnia. Mechanical ventilation can, however, induce or aggravate the lung injury caused by the respiratory distress. Helium, in a gas mixture with oxygen (heliox), has a low d...

OBJECTIVE To compare the risk of neonatal and infant adverse outcomes between vacuum and forceps assisted deliveries. DESIGN Population based study. SETTING US linked natality and mortality birth cohort file and the New Jersey linked natality, mortality, and hospital discharge summary birth cohort file. PARTICIPANTS Singleton live births in the United States (n = 11 639 388) and New Jerse...

BACKGROUND Preterm infants are repeatedly exposed to painful experiences as part of their care in the neonatal intensive care unit. There is evidence from both animal and human studies that exposure to pain during the neonatal period may have persisting consequences for development. OBJECTIVE To perform serial assessments of three heelstick blood draws to examine early changes both in physiol...

OBJECTIVE The aim of the present study was to evaluate the prevalence and factors associated with bronchopulmonary dysplasia at a neonatal intensive care unit. METHODS The study was a cross-sectional study that used secondary data from premature infants who were born with less than 32 weeks of gestational age and were admitted to a neonatal intensive care unit. Chi-square, Mann-Whitney and mu...