Physicians have embraced the concept of dual renin-angiotensin system (RAS) blockade hoping that it would translate into better blood pressure control as well as incremental nephroprotective and cardioprotective effects. With regard to blood pressure, a small additional fall with dual RAS blockade was observed when compared with that seen in monotherapy. Numerous studies have shown a reduction ...

Syzygium polyanthum is traditionally used as anti-hypertensive. However, the nephroprotective effects of S. against hypertensive induced chronic kidney disease remains to be done. This study was conducted determine antioxidant properties and aqueous extract (AESP) in spontaneous rat model (SHR). The phytochemical constituent identified using screening HPLC methods. vitro activities were determi...

Polyalthia longifolia (Sonn.) Thwaites is a traditional medicinal plant with diverse properties including kidney protection. The present investigation was aimed to assess the phytochemical content, antioxidant activity and evaluate nephroprotective of (PL) 70% ethanolic leaf extract against cisplatin gentamicin-induced toxicity on HEK293 cell line. Phytochemical analysis confirmed presence flav...

Graptophyllum pictum is a plant used in medicine from the time of Ayurveda, ancient system Indian medicine. This review article presented to give an insight on all updated information its pharmacological activities. Studies indicated that G. possesses diverse medicinal properties such as anti-inflammatory, nephroprotective, antidiabetic, oxytocic, and anti-implantation properties. comprehends n...

The liver is the organ in charge of homeostasis and metabolism sundry substances (endogenous exogenous, including drugs); but when these are metabolized, they generate more toxic and/or reactive metabolites, that can damage causing cirrhosis, steatosis hepatocarcinoma. Human have been used several medicinal plants (MP) since ancestral times to treat their ailments, diseases disorders, Sylibum m...

BACKGROUND/AIMS Drug-induced acute kidney injury (AKI) has been a severe threat to hospitalized patients, raising the urgent needs to develop strategies to reduce AKI. We investigated the protective activity of Dendropanax morbifera (DP), a medicinal plant which has been widely used to treat infectious and pain diseases, on acute kidney injury (AKI) using cisplatin-induced nephropathic models. ...