1 The pressor responses produced by the intravenous administration of a,#-methylene ATP were tachyphylactic. 2 a,fi-Methylene ATP can attenuate pressor responses to sympathetic nerve stimulation both in the presence and in the absence of a-adrenoceptor blocking agents. 3 a,#-Methylene ATP has no effect on the pressor responses produced by bolus injections of noradrenaline. 4 In the presence of ...

Spinal glial reactivity has been strongly implicated in pain that follows peripheral nerve injury. Among the many therapeutic agents that have been tested for anti-allodynia through immune modulation is the atypical methylxanthine propentofylline. While propentofylline shows a potent anti-allodynia effect after nerve transection injury, we here demonstrate that, when propentofylline is used int...

In order to explore the role of catecholamine and Ca2+ in the synaptic transmission from taste cells to sensory nerve terminals, the effects of various agents added to an artificial solution perfusing the lingual artery on the frog taste nerve responses were examined. The injection of reserpine or guanetidine, which are catecholamine-depleting agents, led to a great reduction of the frog taste ...

Chemical warfare agents were demolished by US soldiers at Khamisiyah, Iraq, in March 1991. The authors investigated postwar morbidity for Gulf War veterans, contrasting those who may have been exposed to low gaseous levels of nerve agents and those unlikely to have been exposed. Cox regression modeling was performed for hospitalizations from all causes and hospitalizations from diagnoses within...

introduction: median nerve (mn), one of terminal branches of brachial plexus, is commonly associated with several variations. this research aimed to review the literature related to the variations of mn from axillary region to cubital fossa. methods: we searched google scholar, science direct, springer, and pubmed electronic databases to compile reports related to the variation of mn published ...

objective(s):  the aim of this study was to evaluate the final outcome of nerve regeneration across the eggsell membrane (esm) tube conduit in comparison with autograft. materials and methods: thirty adult male rats (250-300 g) were randomized into (1) esm conduit, (2) autograft, and (3) sham surgery groups. the eggs submerged in 5% acetic acid. the decalcifying membranes were cut into four pie...

background: carpal tunnel syndrome (cts) is one of the most common musculoskeletal disorders among computer users. computer users exhibit various wrist angles while typing. dynamic changes of wrist angle may cause different degrees of median nerve compression. the objective of this study was thus to investigate the effects of the combination of wrist flexion-extension with wrist deviation on me...

several previous studies of adults have reported that the amplitudes of the sural and superficial radial nerve (sn and srn) action potentials are larger with antidromic than with orthodromic recordings. however, this difference has not been documented in children. this study evaluated the amplitudes of sn and srn sensory nerve action potentials (snaps), obtained with antidromic and orthodromic ...

Basic mechanism of action of organophosphates (OP)/nerve agents is based on acetylcholinesterase (AChE) inhibition and subsequent accumulation of neuromediator acetylcholine at the cholinergic synapses, either peripheral or central, causing cholinergic hyperstimulation and development of symptoms of poisoning, followed by metabolic dysbalance and, without eff ective prophylaxis/treatment leadin...