purpose: to evaluate the correlation between retinal nerve fiber layer (nfl) thickness and visual field parameters in patients with optic atrophy. methods: this study was performed on 35 eyes of 28 patients with optic atrophy. nfl thickness was measured by optic coherence tomography (oct) and visual field analysis was performed by humphrey perimetry. the correlation between nfl thickness and vi...

The axons that make up the optic nerve originate from the retinal ganglion cells and extend from there to the lateral geniculate body. If cellular integrity is interrupted by disease anywhere along the course of an axon, degeneration occurs in both directions from the point of insult. Thus, axon frag­ ments between the site of injury and the lat­ eral geniculate body are separated from their nu...

purpose: to quantify the intraobserver reproducibility of retinal nerve fiber layer (rnfl) measurements using scanning laser polarimetry with variable corneal compensation in glaucoma suspect patients. methods: twenty-six eyes of 26 glaucoma suspect patients were included. complete ophthalmologic examination and standard automated perimetry were performed for all of them. rnfl measurements were...

background: optical coherence tomography (oct) is a simple, high-resolution technique to quantify the thickness of retinal nerve fiber layer (rnfl) and macula volume, which provide an indirect measurement of axonal damage in multiple sclerosis (ms). this study aimed to evaluate oct finding in relapsing-remitting ms patients of the northwest of iran and compare them with a normal control group. ...

A 59-year-old woman was referred to our clinic for a glaucoma evaluation. The visual acuity and intraocular pressure were normal in both eyes. However, red-free fundus photography in the left eye showed a superotemporal wedge-shaped retinal nerve fiber layer defect, and visual field testing showed a corresponding partial arcuate scotoma. In an optical coherence tomography examination, the macul...

BACKGROUND This report details ocular toxocariasis presenting as bilateral scleritis with suspect retinal granuloma in the nerve fiber layer. CASE PRESENTATION The patient presented with scleritis, which did not improve with systemic steroid. Intraocular pressure was elevated, and well demarcated hyper-reflective round lesion were noted in both eyes. He had a history of general ache and concu...

The Retinal Nerve Fiber Layer thickness is one of the main clinical parameter used to diagnose glaucoma eye disease. The thickness of the RNFL decreases as the intraocular pressure inside the eye increases. Decrease in RNFL thickness or damages to RNFL due to high intraocular pressure leads to Glaucoma. The present work provides a technique for the segmentation of Retinal Nerve Fiber Layer (RNF...

PURPOSE To evaluate changes in retinal nerve fiber layer thickness as measured by scanning laser polarimetry (SLP) after the use of medication to reduce intraocular pressure (IOP) in glaucomatous or ocular hypertensive patients. METHODS The authors prospectively enrolled 37 eyes of 37 patients in whom IOP was reduced by more than 25% after the use of medication. The images were obtained befor...

Spectrin is a major component of the mammalian neuronal cytoskeleton. In the CNS, three isoforms of brain spectrin are known to exist: a cellular and dendritic isoform, (240/235E), related to neurons and glia; a cellular and axonal isoform, (240/235), related to neurons; and an isoform specific for astrocytes, (240/235A). In the present study, brain spectrins (240/235E) and (240/235) were local...