Association of dengue fever with transverse myelitis in the form of extensive spinal cord involvement is a rare entity described in the literature. We describe a middle-aged man who presented with dengue fever and in whom weakness of the bilateral lower limbs and urinary incontinence developed on the third day of fever. Magnetic resonance imaging confirmed the diagnosis of longitudinally extens...

Introduction Cryopyrin-associated periodic syndrome (CAPS) is a constellation of diseases with a different and varying clinical spectrum which is rarely seen in childhood. The mildest form of CAPS which is familial autoinflammatory syndrome and the most severe form which is chronic inflammatory neurologic cutaneous arthropathy (CINCA) possess a very different spectrum of clinical findings. Most...

Although the 2009 Swine flu (H1N1) pandemic has apparently been abolished, there are still lessons to be learnt. We reviewed the clinical and pathological manifestations of CNS involvement of influenza A virus infection. Neurologic disorders were most commonly seen as underlying medical conditions in swine flu, and neurological complications of the H1N1 vaccination. The major point with regard ...

We describe a 28-year-old man with presumed VKH syndrome, whose presenting symptoms were bilateral impaired vision and headaches. Orbital MR imaging findings included bilateral choroidal and retrobulbar contrast enhancement, while brain findings included white matter abnormalities on FLAIR and leptomeningeal enhancement. Pachymeningeal enhancement has been described previously; herein, we repor...

Wilson's disease (WD) is a rare autosomal recessive inborn error of copper metabolism caused by a mutation to the copper-transporting gene ATP7B. The presentation is usually neurologic or hepatic, seen in 40% of patients. Diagnosis depends primarily on clinical features, biochemical parameters and the presence of the Kayser-Fleischer ring. Here a case of Wilson disease with various neurological...

Langerhans cell histiocytosis (LCH) is a rare disorder that affects the pediatric population. LCH complicated with a neurologic deficit due to the presence of epidural involvement is a rare condition. We describe the CT imaging features in a 2-year-old boy who presented with drowsy consciousness resulting from an epidural hematoma caused by spontaneous bleeding in an LCH of the skull. CT is an ...

A 54-year-old man died following a 20-year course of intermittent neurologic symptoms. He carried a diagnosis of multiple sclerosis, with most severe involvement thought to be in the spinal cord. At autopsy, two neurenteric (enterogenous) cysts were found to indent the anterior spinal cord -- at the T4 and T11 cord levels. Partial diplomyelia was present in the lumbo-sacral cord. These findings...

background and objective: chronic renal failure (crf) may have many effects on nervous system and manifest as headache, seizure, dialysis disequilibrium syndrome, cerebral hemorrhage, hypertensive encephalopathy, uremic neuropathy, and some neurologic complications of transplantation. in this present study we investigate neurologic disorders in children with crf. methods: in this descriptive, c...

According to time from first manifestation to complete clinical presentation «Acute» onset: time from first symptom to complete clinical presentation is less than 1 month 9% (14 of 27) Among such cases were 4 (14,8%) with delayed (5-14 months) new organ involvement. 3 patients presented with renal involvement: 2 cases of microhematuria, proteinuria in patients without cytostatic therapy; 1 case...

Address correspondence to: Dr. Arunkumar Krishnan, C-137, Karthikeyan salai, Periyar Nagar, Perambur, Chennai-600083, Tamilnadu, India; E-mail: [email protected] Langerhans cell histiocytosis (LCH), previously known as histiocytosis X, encompasses a diverse group of proliferative disorders characterized by infiltration and accumulation of histiocytes and other immune effector cells w...