Objective: To evaluate the prevalence of subclinical neuropathy in intensive and conventional treatment groups at completion of the Diabetes Control and Complications Trial (DCCT). Research Design and Methods: We assessed neuropathy using nerve conduction results obtained at DCCT completion after stratifying the DCCT cohort to exclude subjects with progressively less severe degrees of diagnosab...

OBJECTIVE We sought to evaluate the prevalence of subclinical neuropathy in intensive and conventional treatment groups at completion of the Diabetes Control and Complications Trial (DCCT). RESEARCH DESIGN AND METHODS We assessed neuropathy using nerve conduction results obtained at DCCT completion after stratifying the DCCT cohort to exclude subjects with progressively less severe degrees of...

BACKGROUND AND AIM The diagnosis of peripheral diabetic neuropathy is based on clinical examination. Nerve conduction study (NCS) enables earlier diagnosis, but it is demanding and requires specialised personnel. In an attempt to simplify the procedure, this study aimed to identify a new electrophysiological index, which might correlate with results obtained on standardised NCS in patients with...

Diabetic foot ulcer (DFU) is one of the greatest thoughtful difficulties diabetes, negatively affecting patient's health and socioeconomic status. Around world, diabetes prevalence increasing in both developing developed countries. There are several measures place most countries to limit complications. This review summarizes pathogenic mechanisms that lead diabetic focuses on prevention managem...

Different peripheral neuropathies are linked to paraproteinemia. Anti-myelin-associated glycoprotein (MAG) neuropathy, immunoglobulin or its fragment deposition in the interstitium, light chain amyloidosis (AL amyloidosis) and paraneoplastic mechanisms that cannot be solely attributed deposition, represented by polyneuropathy, organotypic, three main causes of neuropathy correlated with Nerve c...

Background: Diabetic Peripheral Neuropathy (DPN) is a common and difficult complication of diabetes poses significant burden to many diabetics the public health-care system. patients in rural areas have higher risk developing related complications inadequate access proper treatment especially low-income countries. Objectives: To determine prevalence diabetic peripheral neuropathy with Type II N...

CONTEXT AND OBJECTIVE In view of the growing burden of type 2 diabetes mellitus (T2DM) globally and associated microvascular and macrovascular complications, the study was done to assess the prevalence and risk factors for diabetic neuropathy among T2DM patients attending a tertiary care hospital. SUBJECTS AND METHODS T2DM patients' ≥30 years of both gender, presenting to the Medicine Departm...

[Purpose] The effects of vitamin D on the circulating levels of IL-17 and IL-13 were investigated in patients with diabetic peripheral neuropathy, patients with diabetes mellitus type 2 without neuropathy, and healthy controls. [Subjects and Methods] A single-blind controlled clinical study was performed, including70 type 2 diabetic patients with or without diabetic peripheral neuropathy and 33...

The prevalence of various forms of peripheral neuropathy has not been previously assessed in large series of patients with essential mixed cryoglobulinaemia (EMC). Clinical and electrophysiological signs of peripheral neuropathy were observed in 21 of 37 EMC patients, consisting of polyneuropathy in 19, mononeuropathy or multiple mononeuropathy in eight, and both in six. The various forms of pe...

Despite the limited efficacy of current medical treatments, and the fact that they only treat the pain component of chemotherapy-induced peripheral neuropathy (CIPN), until recently there has been little interest in exploring surgical therapies for this condition. This is not at all surprising, because at first blush, it would seem that there is no rationale for a surgical approach to a systemi...