The article by Kwok-Hung Lai [1] obligates us to amplify this issue. For this reason, we will add some additional comments. Impaired drainage of the pancreatic exocrine secretion is one of the most important pathophysiological factors underlying pancreatic inflammation. Anatomical and/or functional obstacles at the choledocum and the sphincter of Oddi are among the most relevant etiopathogenic ...

Over the last 15 years, the ability to measure specific molecules and proteins in the living human brain underwent enormous developments, opening direct windows into neurotransmitter functions and cellular processes associated with health and disease. These techniques are based either on the injection of radioactive moieties whose distribution is recorded with positron emission tomography (PET)...

Cannabis resin (CI) produced a dose-related increase in rat brain serotonin concentrations, whereas restraint stress produced maximal rise of the neurotransmitter concentrations at 1 h, followed by a tendency to normalise by 4 h. The prostaglandin (PG) synthesis inhibitors, diclofenac and paracetamol, antagonized CI and restraint stress induced rise in serotonin concentrations. The findings len...

We are enclosing our written response to the Division of Neuropharmacological Drug Products position paper issued as Docket OON-0088 to support the upcoming March 9,200O Psychopharmacological Drugs Advisory Committee (PDAC) meeting. We are also following the procedures outlined in the Federal Register Notice of this PDAC meeting in order to make an oral presentation at the meeting. if you requi...