From the Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts. Address correspondence to Dr. Schmahmann, Department of Neurology, VBK 915, Massachusetts General Hospital, Fruit St., Boston, MA 02114; [email protected] (E-mail). Copyright 2004 American Psychiatric Publishing, Inc. Disorders of the Cerebellum: Ataxia, Dysmetria of Thought, ...

Little is known about the etiology of neuropsychiatric disorders. The identification of autoantibodies targeting the N-methyl-D-aspartate receptor (NMDA-R), which causes neurological and psychiatric symptoms, has reinvigorated the hypothesis that other patient subgroups may also suffer from an underlying autoimmune condition. In recent years, a wide range of neuropsychiatric diseases and autoan...

Assessing human cerebrospinal fluid (CSF) provides a practical way to conduct longitudinal molecular analyses of changes during the course of neurological disease. Integrated and parallel analyses of neurotransmitters, neuropeptides and proteins in CSF may reveal better insights into complex interaction of numerous cell types in the central nervous system (CNS) at an unprecedented level of comp...

Neuropsychiatric behaviours occur frequently in Alzheimer's disease and other dementias and are thought to arise from the neurodegenerative process. However, it is unclear whether neurodegenerative changes in the hippocampus are associated with neuropsychiatric behaviours such as aggression. In this study, semiquantitative measurements of cell loss, atrophy, neuritic plaque and neurofibrillary ...

A delayed diagnosis of insulinoma remains a clinical issue. Hypoglycemic symptoms can mimic neuropsychiatric disorders such as epilepsy. A 27-year-old woman with a history of epilepsy and anti-epileptic drugs (AEDs) developed repeated seizures and neuropsychiatric symptoms after a 9-year asymptomatic interval. She had received transient treatment with AEDs before the possibility of hypoglycemia...

A begger's colony where a neuropsychiatric extension clinic is being run by NIMHANS, Bangalore, was selected for this study wherein 78 neuropsychiatrically ill inmates and 85 well ones were examined and diagnosed as per I.C.D.-9 and followed up on treatment. A period prevalence of 131.09/1000 serious neuropsychiatric morbidity was found with psychoses, mental retardation and epilepsy being more...

Neuropsychiatric symptoms in Alzheimer's disease (AD) are prevalent, however their relationship with patterns of cortical atrophy is not fully known. Objectives To compare cortical atrophy's patterns between AD patients and healthy controls; to verify correlations between neuropsychiatric syndromes and cortical atrophy. Method 33 AD patients were examined by Neuropsychiatric Inventory (NPI). Pa...

BACKGROUND Brucellosis in humans is an infectious disease which may occur following contact with infected domestic animals or the ingestion of unpasteurized dairy products. It has rarely been described in pregnancy. The diagnosis, neuropsychiatric manifestations, and management of brucellosis in a 3rd-trimester pregnant woman are discussed. CASE A 24-year-old Mexican female, G(3)P(2002), at 3...