Obsessive-compulsive-related cutaneous disease most often includes trichotillomania, neurotic excoriations and nail biting. In this report, we present two cases of self-inflicted severe wounds that were diagnosed as secondary to obsessive-compulsive behaviour. Patients were middle-aged females who presented with deep cutaneous ulcers that were acknowledgedly maintained through repetitive manipu...

Rational emotive behaviour therapists view stress-related disorders as originating in irrational beliefs (iB’s), phirosophies and anitudes, as opposed to the stressor. People who suffer from stress d@erfrom people who suffer from emotional or neurotic problems mainly an that the stressed people have iB’s about specific, short-term or more readdy identifiable events, as opposed w the more mundan...

This report is based on a study of 12 cases of depression (8 endogenous, 4 neurotic) with a view to explore the possible association between urinary melatonin and the illness prior to and following treatment. While cases of endogenous depression had low 24 hour as well as nocturnal urinary melatonin levels, the neurotic depressives showed higher than normal levels. A rise in the 24 hour melaton...

Causes of pain in wound care Dressing-related pain can sometimes be worse than the pain from the wound. Benbow (2010) suggests that wound and dressing-related pain is underestimated and poorly managed and may lead to extended healing times. She identifies that the most common causes of pain include removing dressings that stick to the wound bed, skin stripping of periwound skin and tissue macer...

This article considers the anatomy and physiology of the skin,wound healing, excoriation, maceration, peristomal skin and the importance of periwound protection. The results of a 54-patient study of the use of barrier film forming skin protection in periwound skin are presented and a 10-patient healthy volunteer experimental evaluation. The results confirm the effectiveness of barrier protectio...

We have attempted to determine the chronic effects of doxorubicin, a commonly used anticancer agent, on vascular endothelium using an organ culture system. In rabbit mesenteric arteries treated with 0.3 microM doxorubicin for 7 days, rounding and concentrated nuclei and TUNEL-positive staining were observed in endothelial cells, indicating DNA damage and the induction of apoptosis. However, the...

THE changes in behaviour and feeling which were observed in experiments with the Cambridge Cockpit have been described in a previous paper (Davis, 1946). As had been expected, the effects seen in these experiments appeared essentially similar to those observed in aircrew subjected to the stress of operational flying. The first phase of the effects (namely, preoccupation, excessive activity of a...

This is a reproduction of clinical lectures delivered in 1900, in an agreeable form, but without an index. The teachings are generally sound, as one would expect from Mr. Freyer, but there are a few points to which we take exception. For instance, we cannot agree that "the friction caused by the urinary stream keeps up irritation, and may cause excoriation and ulceration at the seat of strictur...

Introduction NEUROTIC men have been found to differ from normal men in a number of particulars, in the