Background Data: Neurotrophins/peptide mixture is a porcine brain-derived peptide preparation with pharmacodynamic properties similar to those of endogenous neurotrophic factors. No study has evaluated the postoperative role neurotrophins/peptide in recovery postdiscectomy motor weakness. Purpose: This aims evaluate effect treatment on L5 weakness after lumbar discectomy compared placebo. Study...

Peripheral nerve injury is an important cause of disability, that can hinder significantly sensory and motor function. The clinical gold standard for peripheral repair the use autografts, nevertheless, this method has limitations such as donor site morbidity. An emerging alternative to autografts are guide conduits, which used entubulate severed provide guidance directed regeneration tissue. Th...