Restriction Site Mapping is one of the interesting tasks in Computational Biology. A DNA strand can be thought of as a string on the letters A, T, C, and G. When a particular restriction enzyme is added to a DNA solution, the DNA is cut at particular restriction sites. The goal of the restriction site mapping is to determine the location of every site for a given enzyme. In partial digest metho...

The pupose of this paper is modeling of Partial Digest Problem (PDP) as a mathematical programming problem. In this paper we present a new viewpoint of PDP. We formulate the PDP as a continuous optimization problem and develope a method to solve this problem. Finally we constract a linear programming model for the problem with an additional constraint. This later model can be solved by the simp...

Abstract Introduction Schistosomiasis is endemic in Africa, Asia, and South America. The parasite, found freshwater lakes, ultimately deposits eggs the veins around organs including bladder. It causes chronic inflammation resulting fibrosis of urogenital tract malignancy. In UK, cases schistosomiasis are unusual historically confined to immigrant population. patient We present case a British bo...