a binding study of nickel ions by a new recombinant human growth hormone (hgh), produced as an injected drug, has been done at 27˚c in nacl solution (50 mm) using an isothermal titration calorimetry. there is a set of three identical and non-interacting binding sites for nickel ions. the intrinsic dissociation equilibrium constant and the molar enthalpy of binding are 40 μm and -16.5 kj/mol, re...

abstract nickel is a heavy metal distributed ubiquitously in nature. it accumulates in soil as a result of human activities, including mining and industries development. it may be poisonous to plants, humans, animals and microorganisms. the present study was implemented as a factorial experiment with a randomized complete block design (rcbd), of three replications in calcareous soils of karaj a...

A vacuolar H+-ATPase-negative mutant of Saccharomyces cerevisiae was highly sensitive to nickel ion. Accumulation of nickel ion in the cells of this mutant of less than 60% of the value for the parent strain arrested growth, suggesting a role for this ATPase in sequestering nickel ion into vacuoles. An artificially imposed pH gradient (interior acid) induced transient nickel ion uptake by vacuo...

Porous nickel oxide films were prepared by electrochemically precipitating nickel hydroxide and heating the hydroxide in air at 300°C. The resulting nickel oxide films behave as an electrochemical capacitor with a specific capacitance of 59 Flg electrode material. These nickel oxide films maintain high utilization at high rates of discharge (i.e., high power density) and have excellent cycle li...

We investigated the capacity of CD25(+) T regulatory cells (Treg) to modulate T cell responses to nickel, a common cause of allergic contact dermatitis. CD4(+) T cells isolated from the peripheral blood of six healthy, nonallergic individuals showed a limited capacity to proliferate in response to nickel in vitro, but responsiveness was strongly augmented (mean increment +/- SD, 240 +/- 60%) wh...

Metal acquisition is crucial for all cells and for the virulence of many bacterial pathogens. In particular, nickel is a virulence determinant for the human gastric pathogen Helicobacter pylori as it is the cofactor of two enzymes essential for in vivo colonization, urease and a [NiFe] hydrogenase. To import nickel despite its scarcity in the human body, H. pylori requires efficient uptake mech...

to assess nickel-induced toxicity in plants, zea mays seeds were germinated and cultured on nutrient solution with nickel concentrations of 0, 50, 100 and 200 μm for a period of two weeks. its effects on the growth, hill reaction and photosynthetic pigments content were then investigated. the fresh and dry weight of leaves and roots increased in 50 μm nickel, but decreased in 100 and 200 μm. th...

he wide use of nickel coatings is T due to their valuable properties.l-2 Nickel coatings are used primarily for decorative and industrial purposes. The uses of nickel in the decorative field are. numerous including automobile parts, fumiture, general hardware and fasteners, bicycles, as undercoats in low-cost jewelry, sporting equipment, toys, cutlery, lamps and plumbing fixtures. Most of the d...

The oxidation behavior of two types of inhomogeneous nickel was investigated in air at 1273 K for a total oxidation time of 100 h. The two types were porous sintered-nickel and microstructurally inhomogeneous cast-nickel. The porous-nickel samples were fabricated by compacting Ni powder followed by sintering in vacuum at 1473 K for 2 h. The oxidation kinetics of the samples was determined gravi...