CASE HISTORY A 29-yr-old male was seen in clinic for apparent mediastinal lymphadenopathy. While in the USA, 1 month previously, he became unwell, with night sweats, malaise, cough and pleuritic chest pain. He attended hospital, where the unusual appearance of his chest radiograph was noted. Subsequently, computed tomography (CT) of the thorax was undertaken and he was advised that he would nee...

(Chest 1993; 104:251-53) A 23-year-old Hispanic man was admitted for bilateral arm weakness. Two weeks earlier, he had fallen forward on an outstretched left arm and developed pain. One day after visiting a local chiropractor for manipulation ofhis upper arms and back, he noted weakness and numbness in his arms as well as bilateral shoulder pain. There was no lower extremity weakness or bowel o...

Case 1 A 22-year-old aboriginal woman presented with a 12-week history of fever, night sweats, weight loss and productive cough. She had no history of lung disease or any condition known to compromise immune function. Plain chest radiography revealed consolidation and moderate volume loss in the left upper lobe of the lung, with at least 2 cavities at the apex, the largest measuring 4–5 cm in d...

Most patients with tuberculosis of the cervical spine present with localized neck pain and constitutional features like malaise, fever, anorexia, loss of body weight and night sweats, as early symptoms followed by long tract signs, with or without sphincter involvement, as the disease progresses. However, occasionally these patients may present with a radicular pain as an early presenting sympt...

Multicentric Castleman disease (MCD) is a rare nonmalignant lymphoproliferative disorder presenting systemic symptoms such as fever, night sweats, fatigue, anemia, effusions, and multifocal lymphadenopathy. The etiology of MCD has not been clarified to date. The coexistence of MCD with chronic myelomonocytic leukemia (CMML) has been rarely reported. Although the pathogenesis remains unclear, th...

Background: In healthy people infection with Mycobacterium tuberculosis often causes no symptoms since the person’s immune system acts to “wall off” the bacteria. The common symptoms of active TB of the lung are coughing, sometimes with sputum or blood, chest pain, weakness, weight loss, fever and night sweats. If left untreated, each person with active TB disease will infect on an average betw...

A 62-year-old male presented with productive cough, weight loss, and night sweats. CXR revealed a right upper lobe cavitary lesion. Evaluation was negative for Mycobacterium tuberculosis, and sputum revealed Mycobacterium avium intracellulare (MAI). Since his clinical course was atypical for MAI, further investigations were pursued which identified Mycobacterium interjectum in lung specimens, a...

1,2 An 82-year-old male presented with dysphagia to solids and liquids, weight loss, odynophagia and left cervical pain for two months. Fever or night sweats were not reported. An otorhinolaryngological examination revealed permeable nostrils, free cavum, erythema of the arytenoid mucosa, and a suspicion of a malignant lesion in the left arytenoepiglottic fold. No lymphadenopathy of significant...