Between 1999 and 2005, a Task Force composed of CORESTA members has studied the existing methodologies for the determination of the Tobacco Specific Nitrosamines (TSNAs) in the mainstream smoke of cigarettes. Several methods have been proposed for this determination, which are mainly based on two types of analytical methodologies: GC-TEA (Gas Chromatography with a Thermal Energy Analyser as det...

the biodegradation of secondary amines is particularly important due to their propensity for conversion either chemically or microbiologically to n-nitrosamines which are potent carcinogens. in this research, a weak gram-positive organism was isolated from river and identified as mycobacterium. this mycobacterium grows slowly and effectively utilizes piperazine as the sole source of organic, ca...

Tobacco smoking during pregnancy is associated with a variety of negative consequences not only for the mother, but also for the developing fetus. Many studies have shown that carcinogens contained in tobacco smoke permeate across the placenta, and are found in fetus. The aim of the study was to determine the prenatal exposure to tobacco-specific carcinogenic N-nitrosamines on the basis of meas...

This study aims to provide longitudinal and spatial insights to the rejection of N-nitrosamines by reverse osmosis (RO) membranes during sampling campaigns at three full-scale water recycling plants. Samples were collected at all individual filtration stages as well as at a cool and a warm weather period to elucidate the impact of recovery and feed temperature on the rejection of N-nitrosamines...

Many cases of lower urinary tract cancer cannot be attributed to the known risk factors of cigarette smoking and certain occupational chemical exposures. Data from a case-control study conducted on Oahu, Hawaii, from 1979 to 1986 were used to determine the role of several additional exposures in the etiology of lower urinary tract cancer, such as total fluid intake and dietary nitrites and nitr...

The dramatic shift in the pathological presentation of lung cancer [the proportional decrease in squamous cell carcinoma (SCC) and increase in adenocarcinoma (AC)] observed in the United States after the 1950s may have taken place as the result of the reduction in polycyclic aromatic hydrocarbons (PAHs) and the increase in N-nitrosamines in inhaled smoke from filtered low-yield cigarettes. The ...