N-Nitrosodimethylamine is one of the main N-nitroso compound,commonly found in drinking water and is a potent hepatotoxin, carcinogen and mutagen. The curative effect of ethanolic root extract of Operculina turpethum was studied for its possible hepatoprotective potential against NNitrosodimethylamine in Swiss albino mice. Hepatic malondialdehyde (MDA), Superoxide dismutase(SOD),catalase(CAT),g...

Oximes of glucose, xylose, lactose, fructose, and mannose have been prepared. Nitrosation of the oximes of glucose, xylose, and lactose with NaNO2/HCl afforded 2-(beta-glycopyranosyl)-1-hydroxydiazene-2-oxides, which were isolated as salts 13, 22, and 28. Nitrosation of fructose oxime 29 furnished fructose, whereas nitrosation of mannose oxime 30 with NaNO2/HCl afforded the 1-hydroxy-2-(beta-D-...

Increasing levels of nitrate (NO3-) in drinking water in Denmark is of concern due to the possibility of an associated increase in long-term exposure to endogeneously formed N-nitroso compounds. Using a duplicate portion technique in combination with a qualitative description of diet and other background variables, the total nitrate intake in a Danish rural population and the contribution of dr...

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in this work, a procedure for preconcentration of cobalt using dispersive liquid–liquid microextraction (dllme) with the reagent 1-nitroso 2-naphtol as complexing reagent was developed. at ph 4, co(ii) was complexed with 1-nitroso 2-naphtol and extracted into the fine droplets formed when mixing chloroform (extraction solvent), ethanol (disperser solvent) and the sample solution. after extracti...

The carcinogenic potencies of 3,4-dichloro- and 3,4-dibromonitrosopiperdine were compared with that of nitrosopiperidine by feeding to groups of 15 male rats in drinking water. A treatment of 15 weeks with a total of 0.5 mmole of the dichloro compound led to death of all animals before 24 weeks with tumors of the tongue, pharynx, esophagus, nonglandular stomach, nasal turbinates, trachea, bronc...