A novel method is proposed for extracting the mixed-mode cohesive laws of composite materials undergoing delamination with large-scale fibre bridging. In approach, are derived from a potential function expressed in cylindrical coordinates magnitude and phase angle between normal tangential end-openings. The mapped using experimental R-curves terms J-integral describe both crack tip (high tracti...

The tractions that cells exert on a gel substrate from the observed displacements is an increasingly attractive and valuable information in biomedical experiments. The computation of these tractions requires in general the solution of an inverse problem. Here, we resort to the discretisation with finite elements of the associated direct variational formulation, and solve the inverse analysis us...

The focal adhesion protein vinculin connects the actin cytoskeleton, through talin and integrins, with the extracellular matrix. Vinculin consists of a globular head and tail domain, which undergo conformational changes from a closed auto-inhibited conformation in the cytoplasm to an open conformation in focal adhesions. Src-mediated phosphorylation has been suggested to regulate this conformat...

In this paper, we propose a novel mesh deformation approach via manipulating differential properties non-uniformly. Guided by user-specified material properties, our method can deform the surface mesh in a non-uniform way while previous deformation techniques are mainly designed for uniform materials. The non-uniform deformation is achieved by material-dependent gradient field manipulation and ...

A new model, non-uniform deterministic finite automata (NUDFA’s) over general tinite monoids, has recently been developed as a strong link between the theory of finite automata and low-level parallel complexity. Achievements of this model include the proof that width 5 branching programs recognize exactly the languages in non-uniform NC’, NUDFA characterizations of several important subclasses ...

In the present paper, a three dimensional annular developing incompressible laminar flow through 270- degree curved pipe is numerically simulated. The dimensionless governing equations of continuity, momentums and energy are driven in toroidal coordinates. The governing equations are discretized by projection algorithm using forward difference in time and central difference in space. A three-di...