Current clinical practice for patients presenting to the emergency department with a resolved episode of chest pain and no electrographic or biomarker abnormalities is to conduct routine noninvasive testing, in accordance with American College of Cardiology and American Heart Association guidelines. The rationale is to further reduce the risk of missing a myocardial infarction, a major source o...

conclusions patients with chronic hepatitis c and with a ciscun ≤ 1 had a very low rate of cirrhosis while those with a ciscun = 4 had a high risk of cirrhosis. patients with ciscun = 2 or 3 had an intermediate rate of cirrhosis, and therefore needed to perform a liver biopsy to receive a reliable diagnosis. results we enrolled 249 patients who had complete laboratoristic data, and sufficient l...

IMPORTANCE Patients presenting to the emergency department (ED) with chest pain whose evaluation for ischemia demonstrates no abnormalities receive further functional or anatomical studies for coronary artery disease; however, comparative evidence for the various strategies is lacking and multiple testing options exist. OBJECTIVE To compare chest pain evaluation pathways based on their associ...

Noninvasive cardiac imaging is now central to the diagnosis and management of patients with known or suspected chronic coronary artery disease (CAD). Although rest echocardiography has become the most common of the techniques, nuclear cardiology and more recently cardiac computed tomography (CCT) and cardiac magnetic resonance (CMR) play important roles in this regard. This review examines the ...

conclusions fib-4 confirmed the best value for diagnosis of significant fibrosis. apri had a sub-optimal diagnosis accuracy for significant fibrosis. lsm showed the most balance diagnosis value for cirrhosis with the highest sensitivity and moderate specificity. patients and methods a total of 544 patients with chb were assessed for fibrosis stage by four noninvasive tests containing liver stif...

a bstract background: labor is a stressful situation that may have an adverse impact. aromatherapy is a method to control anxiety and stress of women. this study was conducted to investigate the effect of aromatherapy using essential oil of orange on women’s anxiety during labor.   materials and methods: in this clinical trial study, 100 women during labor were randomly assigned to two groups: ...

down syndrome (ds) is a birth defect with huge medical and social costs, caused by trisomy of whole or part of chromosome 21. it is the most prevalent genetic disease worldwide and the common genetic cause of intellectual disabilities appearing in about 1 in 400-1500 newborns. although the syndrome had been described thousands of years before, it was named after john langdon down who described ...

The fluorescence lifetime image of HeLa cells expressing an enhanced green fluorescent protein (EGFP)-fusion protein changes under stress, which allows noninvasive determination of the status of individual cells.

objective(s): there are many reports about the role of rostral ventromedial medulla (rvm) in modulating stress-induced analgesia (sia). in the previous study we demonstrated that temporal inactivation of rvm by lidocaine potentiated stress-induced analgesia. in this study, we investigated the effect of permanent lesion of the rvm on sia by using formalin test as a model of acute inflammatory pa...