MAP2C is a microtubule-associated protein abundant in immature nerve cells. We isolated a cDNA clone encoding whole mouse MAP2C of 467 amino acid residues. In fibroblasts transiently transfected with cDNA of MAP2C, interphase microtubule networks were reorganized into microtubule bundles. To reveal the dynamic properties of microtubule bundles, we analyzed the incorporation sites of exogenously...

Isolated corpus callosum dysgenesis (CCD) is a congenital malformation which occurs during early development of the brain. In this study, we aimed to identify and describe its consequences beyond the lack of callosal fibres, on the morphology, microstructure and asymmetries of the main white matter bundles with diffusion imaging and fibre tractography. Seven children aged between 9 and 13 years...

The rational Pontryagin classes, evaluated on fiber bundles where the is a 2n-dimensional euclidean space, can be nonzero in cohomology dimensions much greater than 4n. This makes striking contrast with classes of vector bundles.

Fibrous Proteins In their Research Article on page 11858, Yuanjin Zhao, Yang Jiao, Fangfu Ye et al. report the organization of collagen fiber bundles. The bundles transmit mechanical signals and induce strongly correlated cell migration.