A patient with Crigler-Najjar disease has survived with the help of phototherapy to the age of 2 years without neurological damage. Because long periods of phototherapy are a threat to normal development, a search was made for supplementary treatments. Cholestyramine and a high fat diet were effective, and possibly also aspartic acid. Maintenance therapy with cholestyramine allowed the amount o...

Background: Various hormone tests of the presence of spermatozoa on testicular sperm extraction (TESE) in azoospermic men have been investigated. Because of its clinical importance, we conducted this study to evaluate complete reproductive serum hormone levels in nonobstructive azoospermic (NOA) patients for determining markers which can predict the spermatogenesis. Materials and Methods: Seven...

The aim of the present work was to present the outcomes of the patients with Y-chromosome microdeletions treated by intracytoplasmic sperm injection (ICSI), either using fresh (TESE) or frozen-thawed (TESE-C) testicular sperm and ejaculated sperm (EJAC). The originality of this work resides in the comparisons between the different types of Y-microdeletions (AZFa, AZFb, and AZFc) and treatments,...

It is well accepted that the presence of nonobstructive atherosclerotic plaques, particularly those with high-risk morphological (HRM) features, is associated with an increased risk of future cardiovascular disease events. This observation has led to proposals to use data on nonobstructive plaque characteristics (if available) to alter the thresholds for prescribing lipid-lowering drugs for pri...

Severe hypercalcemia in the course of renal failure is quite unusual. If unrecognized, irreversible inexorable attrition of renal function takes place, carrying a substantial morbidity and mortality. In particular, acute nonobstructive pyelonephritis is barely considered in the primary differential diagnosis of renal failure. Without urinary obstruction, kidney hypoperfusion, or exposure to nep...

Approximately 1% of all men in the general population suffer from azoospermia, and azoospermic men constitute approximately 10 to 15% of all infertile men. Thus, this group of patients represents a significant population in the field of male infertility. A thorough medical history, physical examination and hormonal profile are essential in the evaluation of azoospermic males. Imaging studies, a...

High-resolution manometry (HRM) is the primary method used to evaluate esophageal motor function. Displayed and interpreted by esophageal pressure topography (EPT), HRM/ EPT provides a detailed assessment of esophageal function that is useful in the evaluation of patients with nonobstructive dysphagia and before foregut surgery. Esophageal motility diagnoses are determined systematically by app...

A 33-year old female was admitted to the hospital presented with right hypochondrium abdominal pain and jaundice. Abdominal ultrasonography showed multiple saccular dilatations of the intrahepatic biliary tract. Endoscopic Retrograde Cholangiopancreatography was performed (Figure 1A) showing nonobstructive saccular or fusiform dilatation of the intrahepatic bile ducts and choledochal cyst. Also...