نتایج جستجو برای: nras
تعداد نتایج: 2055 فیلتر نتایج به سال:
Solution-based ZnO nanorod arrays (NRAs) were modified with controlled N doping by an advanced ion implantation method, and were subsequently utilized as photoanodes for photoelectrochemical (PEC) water splitting under visible light irradiation. A gradient distribution of N dopants along the vertical direction of ZnO nanorods was realized. N doped ZnO NRAs displayed a markedly enhanced visible-...
Abstract Photoelectrochemical photocurrent switching (PEPS) effect can regulate the polarity of photocurrent, which has significant potential applications in areas such as logic gates, photosynapse, and artificial intelligence. In this work, it is reported for first time that a pure Ga 2 O 3 photoelectrochemical system exhibits ambipolar behavior induced by deep ultraviolet, closely linked to c...
Melanocyte PDL1 promotes early tumor progression in a novel autochthonous NRAS-mutant melanoma model
Abstract Tumor-intrinsic PDL1 drives melanoma treatment resistance. Melanocytes (melanoma cell-of-origin) do not express PDL1, but is expressed in malignant melanomas, suggesting melanocyte promotes melanomagenesis. We developed a novel autochthonous mouse model that develops NRAS Q61R-mutant melanomas lacking only melanocytes (PDL1 KOTN Q61R) and littermate controls +/+TN Q61R). induced mice w...
Myelodysplastic syndrome (MDS), is a group of heterogeneous disorders of hematopoietic stem cell colonies which is determined by incomplete hematopoiesis in one or more cell lines. The incidence increases with age and it has less been reported among patients under 50 years of age. The commonest form of MDS is sporadic, and familial occurrence of MDS is rare. Patients with familial MDS are young...
This is a survey of the results obtained by K. G lazek and his co-workers. We restrict our attention to the problems of axiomatizations of n-ary groups, classes of n-ary groups, properties of skew elements and homomorphisms induced by skew elements, constructions of covering groups, classifications and representations of n-ary groups. Some new results are added too.
Vulvar and vaginal melanomas are infrequent malignancies characterized by an aggressive behaviour and a poor prognosis. Surgery is the treatment of choice for primary tumors and loco-regional metastases. As target therapies have emerged as effective treatments both in the advanced and adjuvant settings, molecular profiling of primary tumors and/or metastases is mandatory in order to choose the ...
Analysis of colorectal carcinoma (CRC) tissue for KRAS codon 12 or 13 mutations to guide use of anti-epidermal growth factor receptor (EGFR) therapy is now considered mandatory in the UK. The scope of this practice has been recently extended because of data indicating that NRAS mutations and additional KRAS mutations also predict for poor response to anti-EGFR therapy. The following document pr...
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