Coffee production generates significant amounts of by-products, posing challenges for waste management in the industry. Recent research has revealed that coffee by-products are rich bioactive compounds suitable to produce functional food ingredients and nutraceuticals. In this review, we explore biorefinery strategies extracting utilizing from including bio-based chemicals materials, as well ex...

The demonstration that immune and epithelial cells can discriminate between different microbial and bioactive plant species has extended the known mechanism(s) of action of nutraceuticals and probiotics beyond simple nutrition and/or antimicrobial effects. The progressive unravelling of these plant and bacterial effects on systemic immune and intestinal epithelial cell function has led to new c...

Children with headache have limited evidence-based preventive options. When pharmacological measures are considered, it is not surprising that children are using agents considered to be complementary and alternative in dealing with their headaches. Unfortunately, the use of many of these (and other) headache preventives has outpaced the research which may show clear evidence for their use, or, ...

The management of interstitial cystitis (IC) is predominantly the reduction of the symptoms of frequency, urgency, and pain. Multimodal treatment approaches for IC are helpful in customizing therapy for individual patients. Complementary and alternative therapies are a quintessential addition to the therapeutic armamentarium and frequently include dietary modification, nutraceuticals, bladder t...