The phenomenon of obesity paradox after acute myocardial infarction (AMI) has been reported under strong recommendation of statin therapy. However, the impact of statin therapy on this paradox has not been investigated. This study investigated the impact of statin therapy on 1-year mortality according to obesity after AMI. A total of 2745 AMI patients were included from the Korea Acute Myocardi...

Obesity and heart failure (HF) are twin public health problems. Moreover, obesity can contribute to HF (1). Each contributes to increased mortality. Conversely, weight loss in obese patients without HF improves diastolic function and decreases oxygen requirements and left ventricular (LV) mass (2,3). In two large studies, surgery-induced weight loss reduced cardiac death and improved survival i...

Obesity adversely affects many cardiovascular disease (CVD) risk factors and increases the risk of most CVD, including heart failure (HF). HF is markedly increased in the setting of obesity. However, obese patients with HF have a better prognosis than lean patients with HF, which has been termed the obesity paradox. Therefore, the role of weight loss, which generally improves ventricular struct...

The article written by Zamora et al1 provided an excellent description of the phenomenon known as the obesity paradox in heart failure patients, in this case in a population of heart failure outpatients who had received adequate concomitant treatment for heart failure. Obstructive sleep apnea–hypopnea syndrome (OSAHS) is highly prevalent among the general population and is related to the develo...

The incidence of obesity is steadily increasing, and its prevalence, defined as a body mass index (BMI) above 30 kg/m, is 13% in the world adult population, and rises to up to 40% in high-income countries [1]. As a consequence, around 20% of the patients admitted to the intensive care unit (ICU) are obese [2]. Obesity and overweight are associated with an increased risk of death in the general ...

In 2011, Barclay and Brand-Miller reported the observation that trends in refined sugar consumption in Australia were the inverse of trends in overweight and obesity (The Australian Paradox). Rikkers et al. claim that the Australian Paradox is based on incomplete data because the sources utilised did not incorporate estimates for imported processed foods. This assertion is incorrect. Indeed, na...