In this case series we report four cases of patients with Down syndrome with symptoms consistent with obsessive compulsive disorder. Each patient experienced substantial reduction in compulsive behaviors with pharmacotherapy of an SSRI alone or with the addition of risperidone to SSRI therapy. None of the patients experienced significant side effects. This small case series supports the use of ...

Treatment of obsessive-compulsive-bipolar comorbidity is relatively challenging. This case report presents the improvement of both obsessive-compulsive and mood symptoms in a female patient treated with risperidone plus valproate. Her obsessivecompulsive and manic symptoms, as assessed respectively by using The Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) and Young Mania Rating Scale (YMRS), ...

Background: Obsessive-compulsive disorder (OCD) is associated with heterogeneous and diverse symptoms. A diagnosis challenging when patients experience psychotic This study aimed to evaluate the pattern of symptoms in OCD. Methods: Using semi-structured clinical interviews, 185 meeting DSM-IV diagnostic criteria for OCD were selected. The Yale-Brown Obsessive Compulsive Scale (Y-BOCS) Assessmen...

An emotional Stroop task with four word types (panic threat, obsessive-compulsive threat, general threat, and neutral) and two presentation conditions (supraliminal, subliminal) was used in two experiments. The first experiment involved 21 panic disorder (PD) patients and 20 normal controls; the second experiment 20 PD patients and 20 obsessive-compulsive patients. PD patients, obsessive-compul...

ObjectiveObsessive-compulsive (OC) symptoms are common in the general population, but it is unclear whether subclinical OC and obsessive-compulsive disorder (OCD) part of a neuroanatomical continuum. The goal this study was to investigate relation between subcortical cortical morphology population-based sample children.MethodThe included 2,551 participants, aged 9–12 years, from Generation R St...