discussion the presence of ohss in spontaneous pregnancy especially in familial pattern may lead us to evaluate some endogenous pathogenic factors. case presentation in this case report, we are going to present two cases of ohss occurring in spontaneously conceived pregnancies. one of the patients mentioned the history of this syndrome in her sister, and the other one confronted with this syndr...

background: coasting is the most common method used in the prevention of ovarian hyperstimulation syndrome (ohss) acting through vascular endothelial growth factor (vegf) reduction. however, the pregnancy rate is reported to fall with coasting when it takes more than three days. recently lowdose cabergoline, a selective d2 dopamine receptor agonist has been proven to selectively reduce vascular...

background: the beneficial role of cabergoline as a prophylactic agent to prevent ovarian hyper stimulation syndrome (ohss) among high-risk patients has been demonstrated in previous studies. but data for its role as a treatment for established severe ohss is still limited. we represent the treatment results of high dose oral cabergoline in management of six patients after the syndrome is estab...

This article is a systematic review of the literature on utilization of gonadotrophin-releasing hormone antagonists (GnRH-ant) for ovarian stimulation for IVF in special patient groups. Summarized by meta-analysis are the data from randomized controlled trials (RCT) in which GnRH-agonist (GnRH-a) and GnRH-ant were compared (eight RCT for poor response, four RCT for PCOS). Also reviewed are the ...

Background: Ovarian hyperstimulation syndrome (OHSS) is a rare iatrogenic complication of ovulation stimulation. The pathogenesis of OHSS is uncertain. The crucial event appears to be an increase in capillary permeability by vasoactive mediators such as cytokine and histamine. The aim of this study is to evaluate the role of loratadine (antihistamine) in preventing ovarian hyperstimulation synd...

It is known that most cases of Ovarian Hyperstimulation Syndrome (OHSS) are associated with the therapies for ovulation induction. However, OHSS may rarely be associated with a spontaneous ovulatory cycle, usually in the case of multiple gestations, hypothyroidism or polycystic ovary syndrome. We report a case of severe OHSS in spontaneous pregnancy with invasive mole in a 34 years old woman. T...

Dear Sir, We read with interest the retrospective report by Seyhan et al. (2013) presenting five cases of early ovarian hyperstimulation syndrome (OHSS) in OHSS high-risk patients, following GnRHa trigger and modified luteal phase supportwithonebolusof 1500 IUhCG.Aswehaveperformed the majority of randomized controlled trials (RCTs) in this field, we feel an urge to further comment on the paper,...

Background The aim of the current study is to compare quinagolide with cabergoline in prevention of ovarian hyperstimulation syndrome (OHSS) among high risk women undergoing intracytoplasmic sperm injection (ICSI). MATERIALS AND METHODS This randomized clinical trial study was performed from March 2015 to February 2017. One hundred and twenty six women undergoing ICSI who were at high risk of...

OBJECTIVE To evaluate pregnancy outcomes and the incidence of ovarian hyperstimulation syndrome (OHSS) using a sliding scale hCG protocol to trigger oocyte maturity and establish a threshold level of serum b-hCG associated with optimal oocyte maturity. DESIGN Retrospective cohort. SETTING Academic medical center. PATIENTS Fresh IVF cycles from 9/2004-12/2011. INTERVENTION 10,427 fresh I...