The purpose of this study was to examine the effect of 0-50 micromol/L trans-10, cis-12 conjugated linoleic acid (CLA) and cis-9, trans-11 CLA isomers on lipid and glucose metabolism in cultures of differentiating 3T3-L1 preadipocytes. Specifically, we investigated the effects of 6 d of CLA treatment on the following: 1) (14)C-glucose and (14)C-oleic acid incorporation and esterification into l...

Oleic acid, a monounsaturated, omega-9 fatty acid found in peanut (Arachis hypogaea L.) oil is an important seed quality trait because it provides increased shelf life, improved flavor, enhanced fatty acid composition, and has a beneficial effect on human health. Hence, a concentrated effort has been put forth on developing peanut cultivars that have high oleic acid ( [74%) and a low amount (\ ...

Well-dispersed barium borate nanorods with uniform diameters were synthesized successfully, using Na2B4O7 x 10H2O and Ba(NO3)2 as raw materials and oleic acid as a modifying agent. Oleic acid was used to modify the surface property of nanorods prepared from the precipitation reaction. TEM images confirmed that the synthesized sample presented nanorod morphology with a length of about 200-400 nm...

Radioactive oleic and linoleic..: adds, labeled with 3II'in the ehain and 14C in the carbonyl group, were administered to white ll~ghorn laying hens. Mixture~ fed in separate experiments included: (1) 3H-.and 14C-Iu.iJeled oleic acid, (2) 311_ and 14C-Iabeled linoleic..: acid and (3) eH] oleic acid and r14Cllinoleic acid. The 3H/ 14C ratios of both the neutral lipid and phospholipid fractions f...

The therapeutic efficacy of single-dose intratracheal dexamethasone (2.5 mg/kg) in oleic acid-induced acute lung injury in the rat was established by showing significant improvement in bronchoalveolar lavage parameters and lung compliance at 24 h after oleic acid as compared with animals not treated with oleic acid. An equivalent dose of intraperitoneal dexamethasone demonstrated no therapeutic...

A human replication initiation protein, Cdt1, is a central player in the cell cycle regulation of DNA replication, and geminin down-regulates Cdt1 function by direct binding. It has been demonstrated that Cdt1 hyperfunction resulting from Cdt1-geminin imbalance, for example, by geminin silencing with small interfering RNA, induces DNA re-replication and eventual cell death in some cancer-derive...

In Escherichia coli, a long-chain acyl-CoA is a regulatory signal that modulates gene expression through its binding to a transcription factor FadR. In this study, comparative proteomic analysis of E. coli in the presence of glucose and oleic acid was performed to understand cell physiology in response to oleic acid. Among total of 52 proteins showing altered expression levels with oleic acid p...

Japanese horse chestnut (Aesculus turbinata) seed extract inhibits the activity of cyclooxygenase (COX), but its active constituents have not been identified. In the present study, COX inhibitors were isolated from the hexane extract of this seed by means of 4 steps of liquid chromatography and were identified by gas chromatography/mass spectrometry and nuclear magnetic resonance. The COX inhib...

Supercritical carbon dioxide (SC-CO2) was used as solvent to synthesize oleyl oleate as an analog of Jojoba oil from oleic acid and oleyl alcohol with high conversion (100%) of the acid into ester in a short time of 100 min. Utilizing a low cost solid catalyst, p-toluenesulfonic acid monohydrate (PTSA), the esterification reaction was performed, without any prior preparation step...