Dlx transcription factors are implicated in patterning the mammalian jaw, based on their nested expression patterns in the first branchial arch (primordium for jaw) and mutant phenotypes; inactivation of Dlx1 and Dlx2 (Dlx1/2-/-) causes defects in the upper jaw, whereas Dlx5/6(-/-) results in homeotic transformation of the lower jaw into upper jaw. Therefore, the 'Dlx codes' appear to regionali...

Giant cell lesions of the maxillofacial region constitute a diverse group lesions, which frequently affect lower jaw, and are commonly detected at younger ages, in second third decades life. They can be categorized as aggressive or non-aggressive mainly based on clinical behavior. Management is most through surgical intervention. However, many patients consider surgery to unfavorable due sacrif...

BACKGROUND/AIM Malocclusion of skeletal class III is a complex abnormality, with a characteristic sagital position of the lower jaw in front of the upper one. A higher level of prognatism of the lower jaw in relation to the upper one can be the consequence of its excessive length. The aim of this study was to find the differences in the length of the lower jaw in the children with skeletal clas...

Ameloblastoma is an epithelial odontogenic tumour of the jaw and exhibits diverse microscopic patterns which occurs either singly or in combination with other patterns. Granular cells can occur in various odontogenic and non-odontogenic tumours. Granular cell ameloblastoma is a rare variant of ameloblastoma as making up 1 to 5% of all ameloblastomas that histopathologically has numerous large g...

Mandibular Block Autografts for Alveolar Ridge Augmentation Michael A. Pikos, DDS Coastal Jaw Surgery, 2711 Tampa Road, Palm Harbor, FL 34684, USA Division of Oral and Maxillofacial Surgery, Department of Surgery, The University of Miami, 1611 N.W. 12th Avenue, Miami, FL 33136, USA Ohio State University, 305 West 12th Avenue, Columbus, OH 43218-2357, USA College of Dental Medicine, Nova Southea...

The study aimed at developing a deep-learning (DL)-based algorithm to predict the virtual soft tissue profile after mandibular advancement surgery, and compare its accuracy with mass tensor model (MTM). Subjects who underwent surgery were enrolled divided into training group test group. DL was trained using 3D photographs CBCT data based on surgically achieved displacements (training group). So...

Osteonecrosis of the jaw is an uncommon but potentially serious complication of bisphosphonate therapy in multiple myeloma. Previous studies showed that the presence of one or two minor alleles of the cytochrome P450, subfamily 2C polypeptide 8 gene (CYP2C8) polymorphism rs1934951 was an independent prognostic marker associated with development of osteonecrosis of the jaw in multiple myeloma pa...

Ping-Fu Yang Chau-Yun Chen Li-Chun Kao Cheng-Jen Ma Fang-Ming Chen Hon-Man Chan Che-Jen Huang Jan-Sing Hsieh Jaw-Yuan Wang Division of Gastroenterology and General Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Department of Radiology, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Department of Radiology, Kaohsiung Medical University Hospital, K...

Salivary duct injury can be idiopathic, iatrogenic, or post-trauma and may result in sialocele or fistula. Most injuries regress spontaneously and botulinum toxin A is one of several therapeutic possibilities. We report a case of iatrogenic injury to the parotid duct after Mohs' micographic surgery for a squamous cell carcinoma excision in the left jaw region, treated by injection of botulinum ...

The goal of our research work is to establish mesenchymal osteoprogenitors derived from human jaw periosteum for tissue engineering applications in oral and maxillofacial surgery. For future autologous and/or allogeneic transplantations, some issues must be addressed. On the one hand, animal-free culture conditions have yet to be established. On the other hand, attempts should be undertaken to ...