AIM To evaluate the morphology of the optic nerve head in eyes with pigmentary glaucoma. METHODS Colour stereo optic disc photographs of 62 patients with pigmentary glaucoma and 566 patients with primary open angle glaucoma were morphometrically evaluated. By prestudy selection, mean visual field defect and neuroretinal rim area were not significantly different between the two groups (p = 0.8...

Long-standing vitamin B12 deficiency can lead to neurological manifestations such as optic atrophy and subacute combined degeneration of the cord without causing significant anemia. In addition, folic acid supplementation could mask hematological delay presentation We present a case 32-year-old vegan woman on long-term sodium valproate treatment presenting with progressive weakness bilateral lo...

Demyelination is assumed to be the cause of the majority of cases of isolated optic neuritis. Because of the importance of establishing the presence of optic nerve dysfunction in patients suspected of having multiple sclerosis several new indices of optic nerve conduction have been reported including the visual evoked potential, the edge-light pupil cycle time, and the Pulfrich test. These meas...

Sir, it has been reported that microcysts from macular oedema occur in 4.7% of patients with multiple sclerosis (Gelfand et al., 2012). It is now evident that these microcysts do not represent oedema, nor is their occurrence a specific feature of demyelinating disease, because they have been identified in patients with Leber's hereditary optic neuropathy, Kjer's dominant optic atrophy, and opti...

two brothers with didmoad syndrome are reported. the older brother has diabetes mellitus (type i), diabetes insipidus, optic atrophy, deafness and atonia of the urinary tract with severe symptoms such as diabetic ketoacidosis and frequent urinary tract infections. his younger brother had the same manifestations but with less severity. we report the findings of our two patients and compare them ...

Objective-  To determine the possibility of three-dimensional ultrasonography (3DUS) and measurement of optical nerve sheet by this method. Design- Descriptive study. Animals- 10 mixed normal dogs (5males, 5 females), age 1-1.5 year, and weighting 15±5 kg Procedure- 3D ultrasounds of the eyes were evaluated and the normal optical nerves in 3DUS images were measured using Volouson 730 pro....

Inherited disorders of the optic nerve significantly impact vision in children and adults. The optic nerve disorders most commonly encountered clinically are glaucoma and primary optic neuropathy including Leber's hereditary optic neuropathy (LHON) and autosomal dominant or Kjer's optic atrophy. Current knowledge of the genetics of optic neuropathy and glaucoma makes it possible to test for mut...