A patient with acquired immunodeficiency syndrome (AIDS) developed crytpococcal meningitis, complicated by papilledema and severe progressive visual loss despite medical therapy. Bilateral optic sheath fenestration resulted in significant improvement in vision and resolution of papilledema. Histopathologic evaluation of the optic nerve sheath demonstrated numerous cryptococci. Optic nerve sheat...

OBJECTIVE Optic atrophy is a pathological term applied to optic nerve shrinkage from any process that produces degeneration of axons in the anterior visual system (the retino-geniculate pathway). The pathologist can make the diagnosis of optic atrophy by direct observation of the histopathological changes in the optic nerve. The clinician is restricted to indirect evidence by observing the opti...

Evulsion of the optic nerve is an uncommon traumatic event, probably because the intraorbital portion of the optic nerve is mobile and surrounded by sheaths. The present paper reports a case of complete evulsion of the optic nerve with retinal detachment and discusses the possible patho mechanisms involved. Fluorescein angiography showed no retinal circulation.

The purpose of this study was to determine the temporal and spatial changes in the expression of AQP4 and AQP9 in the optic nerve after it is crushed. The left optic nerves of rats were either crushed (crushed group) or sham operated (sham group), and they were excised before, and at 1, 2, 4, 7, and 14 days later. Four optic nerves were pooled for each time point in both groups. The expression ...

AIM Many approaches for optic nerve decompression have their own advantages and disadvantages. The aim of this study was to perform endoscopic decompression of optic nerve through the supraorbital keyhole and evaluate its feasibility. MATERIAL AND METHODS Ten adult cadaveric heads were studied using 4-mm, 0- and 30-degree rigid endoscopes to perform the optic nerve decompression through the s...

BACKGROUND AND PURPOSE Idiopathic intracranial hypertension is a headache syndrome characterized by increased CSF pressure. Compression of the hypophysis and distension of the optic nerve sheath are reliable imaging signs. The purpose of the study was to validate, in patients with idiopathic intracranial hypertension, MR imaging-based volumetric measurements of the optic nerve sheath and hypoph...

Optic nerve dural ectasia is a rare cause of optic nerve sheath enlargement due to the accumulation of CSF around the optic nerve with no associated pathology. It diagnosed by MRI studies and can follow benign or sometimes an unfavorable course. We describe the case of a 24-day-old female referred for a visual blurring, which we diagnosed as a dural ectasia of the optic nerve sheath by MRI and ...

The vascular aetiology of glaucoma hypothesizes that a compromised blood supply to the optic nerve head contributes to optic nerve head damage. Localized damage may occur when ocular perfusion deficits of the optic nerve head, the retina, the choroid or the retrobulbar vessels falls outside the normal range of autoregulation. This may be the result of systemic dysfunction (vasosclerosis, small ...

The case material of 42 patients with primary tumors of the optic nerve and chiasm examined at our institution within a 10 year period was reviewed. In each case, the radiologic data and certain clinical information were compiled to determine the role of radiology in the workup of patients with these tumors and to compare the results of various imaging methods. Although different types of infor...