Periorificial lentiginosis, also knew as Peutz–Jeghers Syndrome (PJS), is an autosomally dominant inherited condition determined by a mutation localized at 19p13.3 responsible for mucocutaneous pigmentation and gastrointestinal polyps. Skinand mucosal pigmentation may be present at birth but usually occur in early childhood, and occasionally may develop later. Round, oval or irregular patches o...

The objective of this study is the development an in vitro cell culture model pigmented gingival keratinocytes to provide a unique tool assess oral care products such as toothpaste and evaluate whether cells might be less susceptible than unpigmented cytotoxicity by any toothpaste. Sepia melanin at various concentrations was added primary human keratinocyte (HGK) monolayers identify concentrati...

Squamous cell carcinoma (SCC) usually lacks melanocytes within the tumor. A few reports have documented invasive SCC or SCC in situ (intraepithelial neoplasia, IEN) with melanocytic hyperplasia within the tumor, referred to as pigmented SCC, in some organs. However, case series of pigmented SCC or IEN of the esophagus have not yet been reported. This is the first study to analyze the incidence ...

HIGHLIGHTS • Molecular analysis of aurofusarin biosynthesis in F. culmorum. Mycelial pigmentation depending on gene expression and accumulation. Pigmentation variations growth phase.

BACKGROUND Chikungunya fever is caused by chikungunya virus which is transmitted by the bite of infected Aedes aegypti and A. albopictus mosquitoes. AIMS To study the various mucocutaneous manifestations in suspected cases of chikungunya fever. MATERIALS AND METHODS The patients who attended our outpatient department from July 2016 to October 2016 and fulfilled the criteria for "suspect cas...

Dyskeratosis Congenita is a severe disorder that involves several systems in the human body and well-known for its transmission hereditarily through generations. The triad of a) reticular atrophy skin with pigmentation b) dystrophy nails c) leukoplakia oral mucosa characterises this uncommon disorder, which most commonly affects men. One key reasons premature death disease malignant transformat...

AIM Melanin pigmentation of the gingiva occurs in all ethnicities. Excessive pigmentation is an esthetic concern that has increased awareness about de pigmentation procedures. The purpose of the present study was to correlate skin color and gender with intensity and distribution of gingival melanin pigmentation in a group of South Indians. METHODS 200 male and female non smoking healthy subje...

To cite: Thomas J, Subramanyam S, Vijayaraghavan S, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2014208900 DESCRIPTION A 26-year-old man presented with progressive difficulty in swallowing for 2 years and increased skin pigmentation for 1 year. This was associated with a loss of weight despite a preserved appetite. He had a lack of tears since childhood...