The incidence of non-healing ulcer is 1-2 percent in developed countries. In Indian community its prevalence reported year 2004 was 4.8 per 1000 populations. It may increase many folds future because number old persons, diabetes mellitus and vascular diseases
 A male patient aged 63yrs. came to surgery OPD Majeedia Unani Hospital, Jamia Hamdard, New Delhi, October 2019, with the complain o...

Imbalance between exogenous damaging agents and protective factors in the gastro-duodenum tract can lead to peptic ulcer disease. Herbal medicines could be an effective treatment human gastric ulcers. This study aimed investigate effect of AGAR-HP hard capsules on cysteamine-induced gastric-duodenal ulcers experimental rats. The animals were divided into five groups: Group 1 (control) group 2 (...

Leishmaniases are parasitic diseases occurring in endemic tropical and subtropical areas and caused by protozoa of the genus leishmania, transmitted by a diptera (sand fly). We here report a case of topical cutaneous leishmaniasis discovered in a 15-year old boy with painless ulcer on his left leg, who had been staying in South Africa. Clinical examination showed painless non-itchy ulcer, occur...

We report a rare case of association of temporal arteritis with recurrent central corneal ulcer. A 91-year-old male with a remote history of clinically diagnosed giant cell arteritis (GCA) and penetrating keratoplasty (PK) for corneal edema in 1990’s in the left eye presented with irritation and severe dry eye. He progressively developed central corneal ulcer regardless of treatment with aggres...

Gene therapy for gastric cancer and gastric ulcer is a rationalized strategy since various genes correlate with these diseases. Since gene expressions in non-target tissues/cells cause side effects, a selective gene delivery system targeted to the stomach and/or cancer must be developed. The route of vector transfer (direct injection, systemic, intraperitoneal, gastric serosal surface and oral ...

A 65-year-old man who had received an esophagectomy 10 years earlier was admitted to our hospital for right chest pain. Preoperative examinations showed pneumopericardium, a retrosternal gastric tube, and an active gastric tube ulcer. We diagnosed gastropericardial fistula of the gastric tube ulcer. Emergency surgery included lavage and drainage of the pericardial cavity and plombage of the rec...

Tuberculosis of the oral cavity accounts for less than one percent of all cases of tuberculosis, seen in both the primary and secondary stages of the disease. It presents usually as a single, painful, ulcer however, multiple painless ulcers may also be seen. The most common location in the oral cavity is tongue. The palate, buccal mucosa, floor of the mouth, gingiva, and lip are other possible ...

In the present study a hydroalcoholic extract of Syzygium cumini seeds have been investigated for its antioxidant activity in aspirin induced peptic ulcer in rats with the aim of exploring possible correlation between its antioxidant and antiulcer activities. Oxygen free radicals are considered to be important factors in the pathogenesis of peptic ulcer. The level of lipid peroxide was elevated...

The anti-ulcer activity of the oil and mucilage obtained from flaxseed (Linum usitatissimum) was evaluated in a rat model of ethanol-induced gastric ulcer. Our results show that pretreatment of rats with flaxseed oil and flaxseed mucilage significantly reduced the number and length of gastric ulcers induced by ethanol. Flaxseed oil was more effective than flaxseed mucilage in reducing the numbe...

Helicobacter pylori is an important cause of chronic active gastritis and is strongly associated with peptic ulcer disease and gastric cancer. H. pylori colonizes the surface of the gastric epithelium with production of a number of factors, resulting in inflammation and an altered mucosa. H. pylori infection occurs world-wide and the mode of transmission most likely is from human to human via t...