By using otoacoustic emission, we looked for change in outer hair cell (OHC) motile activity and medial olivocochlear (MOC) system inhibition due to benzodiazepine administration, a drug that is known to produce a pharmacological effect by interacting with GABAergic inhibitory neurotransmission. No effect was observed on OHC motile activity, in contrast benzodiazepines decreased MOC system effe...

showed significant changes in frequencies >8 kHz that were not detected with the routine pure tone audiometry and distortion product otoacoustic emission audiodiagnostic tests. In conclusion, although the idea of such studies about the otoprotective effect of intratympanic injections against cisplatininduced ototoxicity seems magnificent and deserves more modifications, a careful revision in ev...

The main purpose of this research was to determine the influence a therapeutic dose an opioid drug (methadone) on selected auditory functions in patients addicted opioids (recognition ICD-10; F11) and undergoing substitution therapy. Various hearing tests were used – pure tone audiometry, impedance otoacoustic emission measurement, speech noise test two sessions, before after methadone intake. ...

To understand how the inner ear-generated sound, i.e., otoacoustic emission, exits the cochlea, we created a sound source electrically in the second turn and measured basilar membrane vibrations at two longitudinal locations in the first turn in living gerbil cochleae using a laser interferometer. For a given longitudinal location, electrically evoked basilar membrane vibrations showed the same...

Several studies have previously demonstrated that postural changes modify evoked otoacoustic emission. In order to evaluate a possible interaction between eye muscles and ciliated cells in the inner ear, we studied the effects of eye lateralization on the contralateral suppression of transient evoked otoacoustic emissions (TEOAEs). Thirty-eight normal hearing subjects with TEOAEs were recruited...

Otoacoustic Emissions (OAEs) are sounds which emerge from ear canal when (paradoxically) tympanic membrane receives vibrations from cochlea transmitted by middle ear. The present study was taken up as the literature review shows that the effect of different click durations on the presence of Transient Evoked Otoacoustic Emission (TEOAE) has not been studied. The present study involved 15 subjec...