Endometriosis, defined by implantation of endometrial tissue outside the uterus, is commonly found on the ovaries and is characterized by a range of symptoms and severity, including chronic pelvic pain and infertility. The role of modifiable exogenous factors such as exercise in the development of this disease is not well understood. The authors conducted a 1990-1994 case-control study (77 case...

In the recent original research published on International Journal of Fertility and Sterility the association between tumor necrosis factor-alpha (TNF-α) genetic polymorphisms and endometriosis in 150 Iranian patients suffered this disease. The authors notably found a lower frequency of TNF-α -863C/A allele A among the affected patients in comparison with healthy women, although this difference...

A 30 year old nulliparous woman, married for 7 years presented with complaints of lower abdominal pain since a year. Her menstrual history has been regular, associated dysmenorrhea. She gave past surgical right ovarian cystectomy in view chocolate cyst noted on diagnostic laparoscopy. Investigations revealed bilateral complex and an elevated Ca-125 100 units/ml, proceeded salphingo-oopherectomy...

CA-125 is a 220-kD cell surface glycoprotein present in over 80% of non-mucinous epithelial ovarian carcinomas and it occurs in the serum of healthy males and females at low concentrations (< 35 U/mL). Serum CA-125 concentration may also be moderately elevated in several benign conditions, such as pelvic inflammatory disease, uterine fibroids, pregnancy, spontaneous abortion with chromosomal ab...

A 41 year old, married for 20 years, presented on 28th May, 2013 with history of dysmenorrhoea, deep dyspareunia, and pelvic pain for the past 6 months. She was nulliparous and practiced contraception by using condoms. Her menstrual pattern was essentially normal and the pain occurred mainly on the first two days of her period. Initial vaginal ultrasound scanning revealed multiple adnexal cysts...