نتایج جستجو برای: oxidized

تعداد نتایج: 24989  

Journal: :journal of the Japan Society for Testing Materials 1953

Journal: :Acta Crystallographica Section C Crystal Structure Communications 1999

Journal: :Journal of agricultural and food chemistry 2011
Wangang Zhang Shan Xiao Eun Joo Lee Dong U Ahn

A total of 120 4-week-old broiler chickens were allotted to 12 pens and fed one of three diets including control, oxidized diet (5% oxidized oil), or antioxidant-added diet (500 IU vitamin E) for 2 weeks. Blood samples were collected at the end of feeding trial, and breast muscles were sampled immediately after slaughter. Breast meats were also collected 24 h after slaughter and used for meat q...

2016
Valérie Plaisance Saška Brajkovic Mathie Tenenbaum Dimitri Favre Hélène Ezanno Amélie Bonnefond Caroline Bonner Valéry Gmyr Julie Kerr-Conte Benoit R. Gauthier Christian Widmann Gérard Waeber François Pattou Philippe Froguel Amar Abderrahmani

Elevated plasma concentration of the pro-atherogenic oxidized low density lipoprotein cholesterol (LDL) triggers adverse effects in pancreatic beta-cells and is associated with type 2 diabetes. Here, we investigated whether the endoplasmic reticulum (ER) stress is a key player coupling oxidative stress to beta-cell dysfunction and death elicited by human oxidized LDL. We found that human oxidiz...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 1999
Y Huang M Mironova M F Lopes-Virella

It has been well documented that acute myocardial infarction is triggered by disruption of atherosclerotic plaques. Immunocytochemistry studies have shown that matrix metalloproteinase-1 (MMP-1) is specifically expressed by cells present in atherosclerotic plaques, including luminal and neovascular endothelial cells. Since MMP-1 degrades type I collagen, a major type of collagen in atherosclero...

Journal: :Transactions of the American Ophthalmological Society 2015
James T Handa Mizuki Tagami Katayoon Ebrahimi Gregor Leibundgut Anna Janiak Joseph L Witztum Sotirios Tsimikas

PURPOSE To test the hypothesis that the accumulation of oxidized phospholipids (OxPL) in the macula is toxic to the retina unless neutralized by a variety of mechanisms, including binding by lipoprotein(a) [Lp(a)], which is composed of apolipoprotein(a) [apo(a)] and apolipoprotein B-100 (apoB). METHODS Human maculas and eyes from two Lp(a) transgenic murine models were subjected to morphologi...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2007
Mikiei Tanaka P Boon Chock Earl R Stadtman

To investigate the effect of RNA oxidation on normal cellular functions, we studied the translation of nonoxidized and oxidized luciferase mRNA in both rabbit reticulocyte lysate and human HEK293 cells. When HEK293 cells transfected with nonoxidized mRNA encoding the firefly luciferase protein were cultured in the presence of paraquat, there was a paraquat concentration-dependent increase in th...

Journal: :The Journal of biological chemistry 2001
S Zieseniss S Zahler I Muller A Hermetter B Engelmann

We analyzed the influence of the atherogenic oxidized low density lipoproteins (LDL) on the activity of the platelet prothrombinase complex, a major contributor to overall thrombin formation in vivo. Platelet dependent thrombin generation was found to be strongly stimulated by in vitro oxidized LDL. The enhancement was additive to that observed with the platelet agonist thrombin. Oxidized LDL i...

Journal: :Geophysical Journal International 1975

Journal: :Japanese Journal of Pharmacology 1998

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