N ickel contam ination of intravenous fluids warrants concern, owing to three specific toxic effects o f Ni2+: (a) cardiac toxic ity , especially increased coronary artery resistance, (b ) oxytocic action on th e u terus, and (c) allergic reactions, since nickel is a common allergen. In ad­ dition, high concentrations of nickel in in trav en o u s flu ids cou ld evoke n o n ­ specific toxic res...

Cholinergic Properties of the Relay Junctions of the Primary Afferent Pathway. D. T. FRAZIER AND L. L. BOYARSKY 1 Monoamine Levels and Neuronal Degeneration in Rat Brain following Lateral Hypothalamic Lesions. ROBERT Y. Moons AND ALFRED HELLER 12 Localization of Tritiated Serotonin in Rat Brain by Electron-Microscopic Autoradiography. GEORGE K. AGHAJANIAN AND FLOYD E. BLOOM 23 The Effect of Dru...

A short survey of the history of ergot, of the original and, for a long time, only source of ergot alkaloids, is given. Once a dreaded poison, ergot has changed its role over the centuries to become a rich treasure house of valuable pharmaceuticals. In the Middle Ages it was the cause of epidemics of ergotism, which cost tens of thousands of people their lives. Ergot was first mentioned by the ...

Cholinergic Properties of the Relay Junctions of the Primary Afferent Pathway. D. T. FRAZIER AND L. L. BOYARSKY 1 Monoamine Levels and Neuronal Degeneration in Rat Brain following Lateral Hypothalamic Lesions. ROBERT Y. Moons AND ALFRED HELLER 12 Localization of Tritiated Serotonin in Rat Brain by Electron-Microscopic Autoradiography. GEORGE K. AGHAJANIAN AND FLOYD E. BLOOM 23 The Effect of Dru...