The influence of phenolic (p-coumaric, caffeic, ferulic, gallic and protocatechuic) acids on glucose and organic acid metabolism by two strains of wine lactic acid bacteria (Oenococcus oeni VF and Lactobacillus hilgardii 5) was investigated. Cultures were grown in modified MRS medium supplemented with different phenolic acids. Cellular growth was monitored and metabolite concentrations were det...

The biogenesis of rosmarinic acid (alpha-O-caffeoyl-3,4-dihydroxyphenyl-lactic acid), the second most common ester of caffeic acid in the plant kingdom, was studied in Mentha arvense and Mentha piperita. Administration of (14)C-labelled compounds showed that, whereas the caffeoyl moiety was formed from phenylalanine via cinnamic acid and p-coumaric acid, the 3,4-dihydroxyphenyl-lactic acid moie...

A reversed-phase liquid chromatographic separation with pulsed amperometric detection of phenolic acids at a glassy carbon electrode is described. Chromatographic separation was carried out in isocratic conditions using 0.20 mol·L-1 acetic acid (pH 5.0)/water (80 : 20, v/v) as mobile phase under constant working potential mode of 0.80 V. Chromatographic peaks presented high resolution and separ...

Cinnamic acid analogs are natural phenolic compounds that have a wide range of biological and therapeutic activities. The present work aimed to predict, through in silico methodologies, the oral bioavailability pharmacokinetic toxicological analyzes for four cinnamic analogues (caffeic acid, ferulic p-coumaric synaptic acid). study revealed good bioavailability, favorable parameters. Virtual Sc...

Controlling the Photoreactivity of the Photoactive Yellow Protein Chromophore by Substituting at the p-Coumaric Acid Group Martial Boggio-Pasqua and Gerrit Groenhof* Laboratoire de Chimie et Physique Quantiques, IRSAMC, CNRS et Universit e de Toulouse, 31062 Toulouse, France Computational Biomolecular Chemistry group, Max-Planck-Institut f€ur Biophysikalische Chemie, Am Fassberg 11, D-37077 G€o...

An electrochemical biosensor based on the immobilization of glucose oxidase into an electropolymerized p-coumaric acid membrane a Pt electrode has been developed and evaluated for detection in range 1 to 30 mM. The exhibits sensitivity 36.96 mA/mMcm2, LOD 0.66 mM, LOQ 2.18 biosensing was by cyclic voltammetry 100 mM phosphates pH 7.00 3% ethanol containing acid. biosensors’ stability, repeatabi...

Tryptanthrin (1), indole-3-acetonitrile (2) and p-coumaric acid methylester (3) were isolated from the aerial parts of Isatis tinctoria L. The compounds show insecticidal and anti-feedant activity against termites (Reticulitermis santonensis), insect preventive and control activity against larvae of the house longhorn beetle (Hylotrupes bajulus) and fungicidal activity against the brown-rot fun...

Objective: In cardiovascular diseases, inflammatory response plays an important role and affects heart function. As a flavonoid compound, p-coumaric acid (pCA), commonly exists in many fruits and vegetables and has a therapeutic effect on inflammatory diseases due to its anti-inflammatory properties. The purpose of the present study was to investigate pCA anti-inflammatory effect and the miRNAs...

Tissue cultures o f Pimpinella anisum and P. major were used to study the biosynthesis o f pseudoisoeugenols. The putative precursors were labelled with 13C with one exception that was labelled with i4C. The incorporation o f the label was controlled by 13C N M R and liquid scintil­ lation, respectively. The biosynthetic sequence found was L-phenylalanine, /-cinnamic acid, /?-coumaric acid, / 7...