Octacalcium phosphate (OCP) has attracted the interest of researchers looking for new biomaterials due to its excellent biocompatibility and high formability. Furthermore, it was an attraction medical combination products that ions molecule doping ability OCP, which originated distinct crystal structure. Then, as antibacterial bone substitute, Ag-substituted OCP (OCP-Ag) a candidate centerpiece...

Many questions remain regarding the formation of ultrathin hydroxapatite (HAP) crystals within the confines of collagen fibrils of bones. These structures form through the interplay of the collagen matrix and non-collagenous proteins, and in vitro mineralization studies employing poly(aspartic acid) (PAsp) as a mimic of the non-collagenous proteins have generated mineralized fibrils with struct...

Amorphous Calcium Phosphate (ACP) is an essential mineral phase formed in mineralized tissues and the first commercial product as artificial hydroxyapatite. ACP is unique among all forms of calcium phosphates in that it lacks long-range, periodic atomic scale order of crystalline calcium phosphates. The X-ray diffraction pattern is broad and diffuse with a maximum at 25 degree 2 theta, and no o...

Osteoarthritis (OA) is the most common form of arthritis that occurs in humans. Despite its prevalence, the pathogenesis of OA is not fully understood. Intraarticular basic calcium phosphate (BCP) (an inclusive term for partially carbonate-substituted hydroxyapatite, octacalcium phosphate and tricalcium phosphate) crystals are implicated in OA and are associated with severe degenerative arthrit...

The chemical composition and binding state of calcium phosphate (CaP) thin films formed on silica substrates were investigated using X-ray photoelectron spectroscopy (XPS). The CaP films were prepared at various treatment periods (such as 15, 30, and 60 min) through contact with an ionic solution supersaturated with calcium and phosphate at 37 o C. These CaP films are denoted as CaP15, CaP30, a...

Bone loss and fractures may call for the use of bone substituting materials, such as calcium phosphate cements (CPCs). CPCs can be degradable, and, to determine their limitations in terms of applications, their mechanical as well as chemical properties need to be evaluated over longer periods of time, under physiological conditions. However, there is lack of data on how the in vitro degradation...