نتایج جستجو برای: p51

تعداد نتایج: 263  

2017
George C. Bitros

The economic constitutions of Germany and Greece have resulted in the postwar period in two economies that are based on two vastly different philosophies. Germany has built a highly competitive, outward looking economy based essentially on the principles of the so-called “Social Market Economy”, whereas Greece has set up a “state-managed economy” by drawing on the principles of central planning...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2012
Kylie Warren Ting Wei Dongsheng Li Fangyun Qin David Warrilow Min-Hsuan Lin Haran Sivakumaran Ann Apolloni Catherine M Abbott Alun Jones Jenny L Anderson David Harrich

Cellular proteins have been implicated as important for HIV-1 reverse transcription, but whether any are reverse transcription complex (RTC) cofactors or affect reverse transcription indirectly is unclear. Here we used protein fractionation combined with an endogenous reverse transcription assay to identify cellular proteins that stimulated late steps of reverse transcription in vitro. We ident...

Journal: :The Journal of biological chemistry 1997
J W Rausch S F Le Grice

Alterations to the highly conserved Asp549 of the retroviral ribonuclease H (RNase H) domain were evaluated in the heterodimeric (p66/p51) reverse transcriptases of human immunodeficiency and equine infectious anemia viruses. In addition to the polymerization-dependent and -independent modes of template hydrolysis, mutants were evaluated via their ability to select and extend the 3' polypurine ...

2016
Peihua Zhang Jin Li Yawei Qi Xudong Tang Jianfeng Duan Li Liu Zeyong Wu Jie Liang Jiangfeng Li Xian Wang Guofang Zeng Hongwei Liu

Tissue inhibitor of metalloproteinases-1 (TIMP-1) is a multifunctional matrix metalloproteinase, and it is involved in the regulation of cell proliferation and apoptosis in various cell types. However, little is known about the effect of TIMP-1 expression on the proliferation of adipose-derived stem cells (ADSCs). Therefore, TIMP-1 expression in the ADSCs was firstly detected by western blottin...

1997
Jürgen Bitzer

National science and technology (S&T) systems are often mentioned as a condition for competitiveness of high technology sectors. Therefore, public S&T policies should actively support the development of national S&T systems. In particular in Eastern Europe an active S&T policy is often demanded to support the development of the supposed domestic "high technology potential". This paper shows tha...

2014

The following information is missing from the Funding section: This work was funded by NIH grant TW009237 as part of the joint NIH-NSF Ecology of Infectious Diseases program and the UK Economic and Social Research Council, and by the Wisconsin Partnership Program through the Wisconsin Center for Infectious Diseases, and the NIH (R01 AI077376-01). This publication was made possible in part by a ...

2005
Ian Lienert Jack Diamond

This Working Paper should not be reported as representing the views of the IMF. The views expressed in this Working Paper are those of the author(s) and do not necessarily represent those of the IMF or IMF policy. Working Papers describe research in progress by the author(s) and are published to elicit comments and to further debate. There has been widespread adoption of new laws to support new...

Journal: :Journal of biomolecular structure & dynamics 2000
R L Jernigan I Bahar D G Covell A R Atilgan B Erman D T Flatow

Abstract By treating an enzyme as a coarse-grained uniform block of material, utilizing only the α-Carbon positions, the normal modes of motion can be obtained. For reverse transcriptase the slower of these motions are suggestive of being involved in the processing step, where the RNA or DNA strand is copied onto a new DNA strand at a polymerase site, and the RNA strand is subsequently cut up...

2006
Guoqiang TIAN

This paper investigates the dimension requirements of informationally decentralized Paretosatisfactory processes in production economies with increasing returns to scale or more general types of non-convexities. We show that the marginal cost pricing (MCP) mechanism is informationally efficient over the class of non-convex production economies where MCP equilibrium allocations are Pareto effici...

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