Although several tendon-selective genes exist, they are also expressed in other musculoskeletal tissues. As cell and tissue engineering is reliant on specific molecular markers to discriminate between cell types, tendon-specific genes need to be identified. In order to accomplish this, we have used RNA sequencing (RNA-seq) to compare gene expression between tendon, bone, cartilage and ligament ...

BACKGROUND Twisting and braiding of four-strand hamstring tendon grafts used for anterior cruciate ligament reconstruction has been proposed, but not proven, as a method of improving tensile properties. HYPOTHESIS Twisting and braiding four-strand human hamstring tendon grafts will have no significant effect on initial graft strength or stiffness. STUDY DESIGN Paired in vitro biomechanical ...

To understand prolotherapy, a knowledge of the pathology of sprain or strain and the normal healing process is necessary. Sprains (ligaments) and strains (tendons) become chronic when healing does not result in sufficient tensile strength or tightness.14,50 This condition also is termed connective tissue insufficiency (CTI), in which the structure is either too loose or has insufficient tensile...

Abstract This report is of an osseous metaplasia the transverse humeral ligament and secondary bicipital tenosynovitis in a 10-year-old Bengal cat. Computed tomography revealed presence bridge enclosing groove, with ultrasonography confirming partial tear inflammation tendon. Initial conservative management intra-articular long-acting steroids failed to provide long-term improvement clinical si...

BACKGROUND The integration of tendon grafts used for replacement of the anterior cruciate ligament is still sometimes unsatisfactory and may be associated with postoperative anterior-posterior laxity. The goal of this study was to examine the capacity of bone morphogenetic protein-2 (BMP-2) gene transfer to improve the integration of semitendinosus tendon grafts at the tendon-bone interface aft...

BACKGROUND The aim of this study was to evaluate the patellar height and degenerative changes of the knee by radiographic assessment after patellar tendon reconstruction for chronic anterior cruciate ligament deficiency. METHODS This series included 44 patients (44 knees) with an average age of 31 years and an average follow up of 58 months. The central one third of the patellar bone-tendon-b...

Ligament reconstruction is an effective therapy for anterior cruciate ligament (ACL) rupture. Polyethylene terephthalate (PET) artificial ligaments have recently gained popularity in clinical ACL reconstruction for its advantage in the improvement of keen function. However, the application of PET in clinical treatment is limited by its poor bioactivity and biocompatibility. Recently, bone marro...

PURPOSE Delayed healing is a common problem whenever tendon allografts are used for tendon or ligament reconstruction. Repopulating the allograft with host cells may accelerate tendon regeneration, but cell penetration into the allograft tendon is limited. Processing the tendon surface with slits that guide cells into the allograft substrate may improve healing. The purpose of this study was to...

OBJECTIVE Demonstrate that the tendon of palmar long can be estimated in relation to its length and width before using it as a graft in surgical procedure. METHODS There were examined 60 forearms of 30 corpses of black ethnicity; measure the length and width of the tendon of the palmaris longus muscle and compared the length of the forearm. RESULTS There are notes their absence unilateral r...

Transthecal digital nerve block is performed by a palmar percutaneous injection of local anaesthetic into the flexor tendon sheath. Total analgesia of the digit is achieved rapidly. This technique was carried out on 46 patients in the accident and emergency department. Successful anaesthesia was obtained in 45 patients. There were no complications.