Eczema is characterized by inflammation of the skin and is commonly associated with food allergy. It has been suggested that nitric oxide (NO) is an important player in eczema, food allergy and intestinal inflammation. The aim of this study was to assess the levels of urinary NO breakdown products in infants with eczema and the effect of eczema treatment on NO levels. Ninety-four infants with e...

BACKGROUND Numerous risk factors have been suggested for hand eczema. This systematic review evaluates the association between tobacco smoking and hand eczema. OBJECTIVE To review the literature systematically on the association between smoking and hand eczema. METHODS The PubMed and EMBASE databases were searched up to 27 January 2015 for articles on the association between tobacco smoking...

This article focuses on several aspects as follows; the relationship between permeability of the gastrointestinal tract and atopic eczema, probiotics and eczema, probiotics and the immune system in the gastrointestinal tract, breastfeeding and immunomodulation, and the relation between breastfeeding and the development of atopic eczema. It is concluded that there is evidence that some probiotic...

Background Eczema (syn. atopic dermatitis, atopic eczema) is a chronic, itchy, skin disease that commonly starts in childhood. Over 500 randomised controlled trials of eczema treatment have been conducted, but a core outcome set is lacking, leading to inefficiency and waste. The Harmonizing Outcome Measures for Eczema (HOME) initiative seeks to agree a core set of outcomes for future research, ...

IL-18 has been found to be associated with eczema. However, little is known of the role of IL-18 binding protein (BP) and IL-18 receptor (R) in eczema. We therefore investigated the expression of IL-18, IL-18BP, and IL-18R on mast cells by using flow cytometry analysis and mouse eczema model. The results showed that plasma free IL-18 and free IL-18BP levels in eczema patients were higher than t...

Background Contact allergy is present in 58-67% children with chronic eczema, yet some children with contact allergy never develop eczema. To assess the significance of contact allergy in eczema, rates of sensitization to each hapten should be compared between eczema patients and general ("healthy”) population. It seems reasonable that haptens with higher odds ratios and attributed risk for sen...

BACKGROUND Hand eczema is a common and distressing condition with multiple causes such as atopy, irritant and allergic contact dermatitis. Fumaria parviflora, is known as Shahtareh in Persian, is a folk medicine for eczema. This study aimed to evaluate the effect of alcoholic extract of Fumaria parviflora on hand eczema. METHODS In a randomized double-blind, placebo-controlled study, 44 patie...