The transactivating isoforms have similar actions with p53, while the N-isoforms inhibit transcription activation by p53 and transactivating isoforms. p63 is expressed in stratified epithelia and in basal cells of the prostate and salivary glands. In mammary epithelium p63 has been shown to be expressed only in the myoepithelial layer. In the present study we investigated the immunohistochemica...

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/ by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Tumor-to-tumor metastasis (TTM) is a rare phenomenon first reported several decades ago in ...

Intracardiac papillary endothelial hyperplasia is seen very rare in the literature. This report describes the case of a 65-year old male patient who had intracardiac neoplasm behind the right coronary aortic cusp. The lesion was treated successfully by surgical excision. According to histopathological analysis the diagnosis was papillary endothelial hyperplasia. The patient was discharged witho...

hamartoma of the breast is a rare benign breast lesion which is unfamiliar to most clinicians, although the mammographic features are usually characteristic. hamartomas are composed of ducts, lobules, fat and fibrous tissue. these benign lesions are likely to be increasingly diagnosed because of routine screening and hence clinical awareness is paramount to prevent these lesions from being over...

The incidence of papillary carcinoma arising in a thyroglossal duct cyst is rare and occurs less than 1% of thyroglossal cysts. We report a case of cystic swelling in the mid-line neck in a young female patient. Fine needle aspiration of the cyst revealed colloid material and macrophages CT scan showed a cystic lesion with calcification. Histopathological examination of the cyst showed papillar...

Context. One of the characteristic findings of intraductal papillary mucinous neoplasms (IPMN) is the presence of a direct communication between the lesion and the ductal pancreatic system and when magnetic resonance cholangiopancreatography (MRCP) shows uncertain findings, it is useful to perform a MRCP after secretin stimulation (MRCP-S) which provides a better visualization of the ductal sys...

BACKGROUND Skull calvarium and dura mater are rare sites of distant metastasis, and mostly have been reported in lung, breast, and prostate malignancies. However, the calvarial and dural metastases from papillary thyroid cancer (PTC) are rare entities and pose diagnostic and therapeutic challenges. To date, only seven cases of calvarial metastasis with intracranial extension from PTC have been ...

introduction struma ovarii is an ovarian teratoma, represented in more than 50% by thyroid tissue. five percent of struma ovarii cases have been proven to be malignant and, as in the thyroid gland, papillary thyroid carcinoma is the most common histotype arising in struma ovarii. because of the unusual occurrence of this tumor, its management and follow-up after pelvic surgery is still controve...

We report a case of intracystic papillary carcinoma of the right breast in a 59-year old man presenting with bloody nipple discharge for 1 week prior to presentation. Mammography, ultrasonography, and core needle aspiration were consistent with intracystic papillary carcinoma. The patient underwent right simple mastectomy. Pathology was also consistent with low grade intracystic papillary carci...