The groundwater flow problem in GFLOW is formulated in terms of the analytic element method (AEM), which is a variant of the Boundary Integral Equation Method (BIEM). Within the AEM a solution is sought for the a priory unknown “strength” parameters of the analytic elements. The strength parameter of a line-sink is its extraction rate σ [m/day], which is constant along the line-sink (Haitjema, ...

Cell-penetrating peptides (CPPs) have emerged as a group of remarkable delivery vectors for various hydrophilic macromolecules, otherwise excluded from cells due to the protective plasma membrane. Unbiased conclusions regarding e.g. uptake mechanism, intracellular distribution and cargo delivery efficacy is complicated by the use of different methodological parameters by different laboratories....

OBJECTIVE The lower recommended age of the donor cornea is a controversial matter. Although newborn corneas have a high endothelial cell density, there are anatomical, refractive (myopic shift) and postoperative problems. Two cases are analyzed; one had an atypical refractive result and the other an unexpectedly severe immune response. We also review the use of pediatric donor corneas in penetr...

Introduction: Laryngotracheal trauma is a rare life-threatening emergency that requires early identification and immediate intervention. Here, we present 26 patients with laryngotracheal trauma from a tertiary hospital in India. The aim was to describe the clinical presentation and management of laryngotracheal trauma patients.   Materials and Methods: This was a retrospective study of laryngot...

Penetrating neck injuries are potentially dangerous and require emergent management because of the presence of vital structures in the neck. Penetrating vascular trauma to zone I and III of the neck is potentially life-threatening. An accurate diagnosis and adequate surgical intervention are critical to the successful outcome of penetrating trauma in the neck. We experienced some cases with ext...

purpose: to compare intraocular pressure (iop) readings measured by the ocular response analyzer (ora) with those measured by the goldmann applanation tonometer (gat) in keratoconic eyes following penetrating keratoplasty (pkp) and to evaluate the influence of anatomical and biomechanical properties of the grafts on iop measurements. methods: this cross-sectional study was conducted on 45 kerat...

purpose: to determine the indications for penetrating keratoplasty (pk) in iran over an 11-year period. methods: all eye bank records of patients who underwent pk from 1994 to 2004 at ophthalmologic centers throughout iran were reviewed. results: during this 11-year period, a total of 19,668 cases were operated. the most common indication for penetrating keratoplasty was keratoconus (34.5%), fo...

Penetrating aortic ulcers were initially described by Shennan in 1934 [1]. Shumacker and King reported the first operative repair of a ruptured descending aorta secondary to a penetrating aortic ulcer in 1959 [2]. The clinical and pathologic entity of penetrating aortic ulcers was not established, however, until 1986 by Stanson [3]. Since that time, the body of literature on this disease has in...

introduction: there are significant gender differences in the epidemiology and presentation of cardiovascular diseases (cvds), physiological aspects of cvds, response to diagnostic tests or interventions, and prevalence or incidence of the associated risk factors. considering the independent influence of gender on early dire consequences of such diseases, this study was conducted to investigate...

in any patient with a history of penetrating thoracic trauma, cardiac injury must be kept in mind. here, we describe a 36 years-old female referred to this hospital with severe chest pain and hypotension. after primary evaluation and suggestion of ami, streptokinase was started for the patient and because of deterioration of vital signs, cardiac surgery consultation was requested. after perform...