In this survey, opsonization activity of sera in 110 patients with meningitis, sepsis and recurrent infection 12 patients after healing and 50 normal adults has been studied. Opsonization activity was measured by an assay depending on electronic particle counting to measure yeast uptake (alternative pathway activator) which was modified in our laboratory. Three classes of immunoglobulins (...

I read with great interest the recent article by Rhee et al. (“Improving documentation and coding for acute organ dysfunction biases estimates of changing sepsis severity and burden: a retrospective study”) in Critical Care [1]. The sensitivity of coding for acute organ dysfunction is increasing over time. More organ dysfunction codes are being captured. This change is the result of pressures o...

The systemic infection has continuously concerned the medical world, due to the impact it has in the complication and aggravation to exitus of certain affections that exceed the ability to respond of the organism. I started the statistic study with a demographic descriptive selection of the lot. The first criterion was the yearly distribution of the study cases. Between 2007 and 2008, 94 cases ...

BACKGROUND Widely studied for the past 20 years, hepatocyte growth factor (HGF) has been identified as a regenerative marker and an important factor in the development and healing of injuries. Antithrombin III (AT III) is a protein in the blood stream with anti-thrombotic and anti-inflammatory properties and has been used as an adjuvant treatment along with antibiotics in severe sepsis. OBJEC...

This is a hospital based cross sectional study to evaluate the validity of septic screen in detecting neonatal sepsis conducted over Nov 2012 to Nov 2013. 60 newborns admitted with suspected sepsis on the basis of clinical presentation were enrolled for the study. All the babies underwent septic screen (TLC, ANC, CRP, I/T Ratio, Platelet count and micro ESR) and Blood culture. Septic screen was...

BACKGROUND Neonatal sepsis is characterised by bacteraemia and clinical symptoms caused by microorganisms and their toxic products. Gram negative bacteria are the commonest causes of neonatal Sepsis. The resistance to the commonly used antibiotics is alarmingly high. The major reason for emerging resistance against antibiotics is that doctors often do not take blood cultures before starting ant...

Objectives: Infections in infants<90 days old are the leading cause of morbidity and hospitalization in neonatal practice. The etiological agents of sepsis (with or without meningitis) in Saudi neonates <90 days old are vastly undercharacterized. The aim of this study was to determine the bacterial etiology of neonatal sepsis and meningitis in these infants. Materials and methods: This retrospe...

Background: Neonatal sepsis is a generalized bacterial infection which occurs in the first month of life. Intraventricular hemorrhage is the most common intracerebral disorder which occurs in premature neonates. Mean Platelet Volume (MPV) is considered as a marker of intraventricular hemorrhage (IVH) in some studies. The aim of this study was to evaluate the impact of MPV on IVH and sepsis in n...

Background Globally, 4 million neonates die annually, with one-third of such deaths occurring as a result of infections. In 2011, there were 7.2million deaths in children below 5 years globally, and a proportion of 40% of these deaths occurred in neonates. Sepsis was reported to account for one-third of these deaths. Presently, multidrug antibiotic resistance is rapidly increasing in Neonatal I...